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    inv1 external invertase, beta-fructofuranosidase Inv1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539227, updated on 18-Sep-2024

    Summary

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    Official Symbol
    inv1
    Official Full Name
    external invertase, beta-fructofuranosidase Inv1
    Primary source
    PomBase:SPCC191.11
    Locus tag
    SPOM_SPCC191.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See inv1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1723434..1726164)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene glutathione S-transferase Gst1 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Schizosaccharomyces pombe inv1+ regulatory region is unusually large and contains redundant cis-acting elements that function in a SAGA- and Swi/Snf-dependent fashion. Ahn S, et al. Eukaryot Cell, 2012 Aug. PMID 22707486, Free PMC Article
    2. Isolation and characterization of glucose derepressed invertase mutants from Schizosaccharomyces pombe. Kig C, et al. Biosci Biotechnol Biochem, 2005 Dec. PMID 16377914
    3. Purification and characterization of the invertase from Schizosaccharomyces pombe. A comparative analysis with the invertase from Saccharomyces cerevisiae. Moreno S, et al. Biochem J, 1990 May 1. PMID 2187435, Free PMC Article
    4. Isolation and characterization of an invertase and its repressor genes from Schizosaccharomyces pombe. Tanaka N, et al. Biochem Biophys Res Commun, 1998 Apr 7. PMID 9535817
    5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. 5' UTR of inv1 gene contains redundant cis-acting elements and requires trans-acting coactivators SAGA and Swi/Snf for glucose-dependent transcription regulation.
      Title: The Schizosaccharomyces pombe inv1+ regulatory region is unusually large and contains redundant cis-acting elements that function in a SAGA- and Swi/Snf-dependent fashion.
    2. wild-type level glucose uptake is essential for the full-level repression of inv1 expression
      Title: Isolation and characterization of glucose derepressed invertase mutants from Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables beta-fructofuranosidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables sucrose alpha-glucosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sucrose alpha-glucosidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sucrose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sucrose catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular region ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    external invertase, beta-fructofuranosidase Inv1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1723434..1726164
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023290.3 → NP_588300.1  external invertase, beta-fructofuranosidase Inv1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588300.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59852, P78891
      Conserved Domains (3) summary
      COG1621
      Location:67 → 577
      SacC; Sucrose-6-phosphate hydrolase SacC, GH32 family [Carbohydrate transport and metabolism]
      pfam00251
      Location:87 → 407
      Glyco_hydro_32N; Glycosyl hydrolases family 32 N-terminal domain
      cl07030
      Location:484 → 538
      Glyco_hydro_32C; Glycosyl hydrolases family 32 C terminal
    Nucleotide Protein
    Heading Accession and Version

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