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    ppn1 cleavage and polyadenylation specificity factor complex-associated protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539414, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ppn1
    Official Full Name
    cleavage and polyadenylation specificity factor complex-associated protein
    Primary source
    PomBase:SPCC74.02c
    Locus tag
    SPOM_SPCC74.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ppn1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003421.2 (1924680..1928307, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene rrm type RNA-binding protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SNARE-binding protein Sly1 Neighboring gene ncRNA Neighboring gene serine/threonine protein kinase AMPK catalytic (alpha) subunit Ssp2 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure-function analysis of fission yeast cleavage and polyadenylation factor (CPF) subunit Ppn1 and its interactions with Dis2 and Swd22. Benjamin B, et al. PLoS Genet, 2021 Mar. PMID 33711009, Free PMC Article
    2. RNA polymerase II CTD interactome with 3' processing and termination factors in fission yeast and its impact on phosphate homeostasis. Sanchez AM, et al. Proc Natl Acad Sci U S A, 2018 Nov 6. PMID 30355770, Free PMC Article
    3. Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1. Schwer B, et al. Proc Natl Acad Sci U S A, 2021 Aug 17. PMID 34389684, Free PMC Article
    4. Genetic screen for suppression of transcriptional interference reveals fission yeast 14-3-3 protein Rad24 as an antagonist of precocious Pol2 transcription termination. Garg A, et al. Nucleic Acids Res, 2022 Jan 25. PMID 34967420, Free PMC Article
    5. CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing. Vo TV, et al. Cell Rep, 2019 Jul 2. PMID 31269446, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of DPS complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    part_of mRNA cleavage and polyadenylation specificity factor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mRNA cleavage and polyadenylation specificity factor complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    cleavage and polyadenylation specificity factor complex-associated protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1924680..1928307 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023366.3 → NP_588375.1  cleavage and polyadenylation specificity factor complex-associated protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588375.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14392, O74535
    Nucleotide Protein
    Heading Accession and Version

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