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    chs2 chitin synthase-like protein 2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540176, updated on 18-Sep-2024

    Summary

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    Official Symbol
    chs2
    Official Full Name
    chitin synthase-like protein 2
    Primary source
    PomBase:SPBC1709.01
    Locus tag
    SPOM_SPBC1709.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPBC1734.17
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    Genomic context

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    See chs2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (1095221..1098228)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene RSC complex bromodomain subunit Rsc4 Neighboring gene SIN3 family co-repressor, Clr6 and Rpd3L histone deacetylase complex subunit Pst3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene valine--tRNA (Val) ligase Vrs1/Vas1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In Schizosaccharomyces pombe chs2p has no chitin synthase activity but is related to septum formation. Martín-García R, et al. FEBS Lett, 2003 Aug 14. PMID 12914947
    2. Genetic analysis of chs1+ and chs2+ encoding chitin synthases from Schizosaccharomyces pombe. Matsuo Y, et al. Biosci Biotechnol Biochem, 2004 Jul. PMID 15277753
    3. Fission yeast Cyk3p is a transglutaminase-like protein that participates in cytokinesis and cell morphogenesis. Pollard LW, et al. Mol Biol Cell, 2012 Jul. PMID 22573890, Free PMC Article
    4. The fission yeast Chs2 protein interacts with the type-II myosin Myo3p and is required for the integrity of the actomyosin ring. Martín-García R, et al. J Cell Sci, 2006 Jul 1. PMID 16772338
    5. Involvement of Smi1 in cell wall integrity and glucan synthase Bgs4 localization during fission yeast cytokinesis. Longo LVG, et al. Mol Biol Cell, 2022 Feb 1. PMID 34910579, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Chs2p participates in the correct functioning of the medial ring.
      Title: The fission yeast Chs2 protein interacts with the type-II myosin Myo3p and is required for the integrity of the actomyosin ring.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables chitin synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chitin synthase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic division septum assembly IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cell periphery IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cell septum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in division septum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chitin synthase-like protein 2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1095221..1098228
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021342.3 → NP_595434.1  chitin synthase-like protein 2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595434.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74756, Q9US88
      Conserved Domains (3) summary
      COG1215
      Location:365 → 751
      BcsA; Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility]
      pfam01644
      Location:255 → 416
      Chitin_synth_1; Chitin synthase
      pfam08407
      Location:182 → 252
      Chitin_synth_1N; Chitin synthase N-terminal
    Nucleotide Protein
    Heading Accession and Version

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