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    sld5 GINS complex subunit Sld5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541368, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sld5
    Official Full Name
    GINS complex subunit Sld5
    Primary source
    PomBase:SPBP4H10.21c
    Locus tag
    SPOM_SPBP4H10.21C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See sld5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2913472..2914295, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene calreticulin/calnexin-like protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene m7G(5')pppN diphosphatase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Rnase P/MRP subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CDK promotes interactions of Sld3 and Drc1 with Cut5 for initiation of DNA replication in fission yeast. Fukuura M, et al. Mol Biol Cell, 2011 Jul 15. PMID 21593208, Free PMC Article
    2. Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins. Yabuuchi H, et al. EMBO J, 2006 Oct 4. PMID 16990792, Free PMC Article
    3. Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components. Kanke M, et al. EMBO J, 2012 May 2. PMID 22433840, Free PMC Article
    4. DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast. Handa T, et al. Mol Biol Cell, 2012 Aug. PMID 22718908, Free PMC Article
    5. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in double-strand break repair via break-induced replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic DNA replication initiation IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of GINS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    GINS complex subunit Sld5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2913472..2914295 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022114.3 → NP_596195.1  GINS complex subunit Sld5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596195.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P7C8
      Conserved Domains (3) summary
      cd11711
      Location:19 → 138
      GINS_A_Sld5; Alpha-helical domain of GINS complex protein Sld5
      COG5086
      Location:1 → 214
      COG5086; Uncharacterized conserved protein [Function unknown]
      pfam16922
      Location:161 → 214
      SLD5_C; DNA replication complex GINS protein SLD5 C-terminus
    Nucleotide Protein
    Heading Accession and Version

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