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    hse1 ESCRT-0 subunit protein HSE1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540055, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hse1
    Official Full Name
    ESCRT-0 subunit protein HSE1
    Primary source
    PomBase:SPBC1734.08
    Locus tag
    SPOM_SPBC1734.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See hse1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (1074379..1075953)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene DNAJ protein Spf31 Neighboring gene TRAPP III complex subunit Trs8502 Neighboring gene postreplication repair E3 ubiquitin-protein ligase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene NST UDP-N-acetylglucosamine transporter Neighboring gene mRNA processing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Schizosaccharomyces pombe Sst4p, a conserved Vps27/Hrs homolog, functions downstream of phosphatidylinositol 3-kinase Pik3p to mediate proper spore formation. Onishi M, et al. Eukaryot Cell, 2007 Dec. PMID 17951524, Free PMC Article
    2. Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe. Iwaki T, et al. Microbiology (Reading), 2007 Aug. PMID 17660439, Free PMC Article
    3. TORC2 inhibition of α-arrestin Aly3 mediates cell surface persistence of S. pombe Ght5 glucose transporter in low glucose. Toyoda Y, et al. J Cell Sci, 2021 May 15. PMID 34028542
    4. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore-type prospore assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in late endosome to vacuole transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ESCRT-0 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ESCRT-0 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in Golgi apparatus HDA PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in fungal-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ESCRT-0 subunit protein HSE1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1074379..1075953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021333.3 → NP_595425.1  ESCRT-0 subunit protein HSE1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595425.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74749
      Conserved Domains (3) summary
      smart00288
      Location:9 → 140
      VHS; Domain present in VPS-27, Hrs and STAM
      cd11805
      Location:219 → 271
      SH3_GRB2_like_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2 (GRB2) and related proteins
      pfam03127
      Location:297 → 362
      GAT; GAT domain
    Nucleotide Protein
    Heading Accession and Version

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