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    mpp6 nuclear exosome-associated RNA binding protein Mpp6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542214, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mpp6
    Official Full Name
    nuclear exosome-associated RNA binding protein Mpp6
    Primary source
    PomBase:SPACUNK4.11c
    Locus tag
    SPOM_SPACUNK4.11C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mpp6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (2890076..2890887)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene metallopeptidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene glyoxylate reductase Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex. Weick EM, et al. Cell, 2018 Jun 14. PMID 29906447, Free PMC Article
    2. The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway. Malecki M, et al. EMBO J, 2013 Jul 3. PMID 23503588, Free PMC Article
    3. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
    4. Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome. Telekawa C, et al. Nucleic Acids Res, 2018 Nov 30. PMID 30321377, Free PMC Article
    5. Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex. Egan ED, et al. RNA, 2014 Jun. PMID 24713849, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to RNA exonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in maturation of 5.8S rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nuclear mRNA surveillance ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in polyadenylation-dependent RNA catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of nuclear exosome (RNase complex) ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    nuclear exosome-associated RNA binding protein Mpp6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2890076..2890887
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019394.3 → NP_593967.1  nuclear exosome-associated RNA binding protein Mpp6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593967.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14076
      Conserved Domains (1) summary
      pfam10175
      Location:2 → 140
      MPP6; M-phase phosphoprotein 6
    Nucleotide Protein
    Heading Accession and Version

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