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    pef1 cyclin-dependent protein kinase Pho85/PhoA-like Pef1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539366, updated on 14-Nov-2024

    Summary

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    Official Symbol
    pef1
    Official Full Name
    cyclin-dependent protein kinase Pho85/PhoA-like Pef1
    Primary source
    PomBase:SPCC16C4.11
    Locus tag
    SPOM_SPCC16C4.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    p31
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    Genomic context

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    See pef1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (687735..688671)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA polymerase epsilon Dpb3 Neighboring gene 6-phosphogluconolactonase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene NatB N-acetyltransferase complex catalytic subunit Naa20

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and preliminary characterization of p31, a new PSTAIRE-related protein in fission yeast. Tournier S, et al. Yeast, 1997 Jun 30. PMID 9219337
    2. The S. pombe CDK5 ortholog Pef1 regulates sexual differentiation through control of the TORC1 pathway and autophagy. Matsuda S, et al. J Cell Sci, 2020 Sep 9. PMID 32788233
    3. Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants. Chen BR, et al. PLoS One, 2013. PMID 23874875, Free PMC Article
    4. A pcl-like cyclin activates the Res2p-Cdc10p cell cycle "start" transcriptional factor complex in fission yeast. Tanaka K, et al. Mol Biol Cell, 2000 Sep. PMID 10982385, Free PMC Article
    5. Search for kinases related to transition of growth polarity in fission yeast. Koyano T, et al. Biosci Biotechnol Biochem, 2010. PMID 20501954

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes.
      Title: The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes.
    2. The S. pombe CDK5 ortholog Pef1 regulates sexual differentiation through control of the TORC1 pathway and autophagy.
      Title: The S. pombe CDK5 ortholog Pef1 regulates sexual differentiation through control of the TORC1 pathway and autophagy.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of sister chromatid cohesion EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulation of cell cycle phase transition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signal transduction IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in traversing start control point of mitotic cell cycle IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in ascospore-type prospore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent protein kinase Pho85/PhoA-like Pef1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      687735..688671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022912.2 → NP_587921.1  cyclin-dependent protein kinase Pho85/PhoA-like Pef1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587921.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74456
      Conserved Domains (2) summary
      PLN00009
      Location:3 → 285
      PLN00009; cyclin-dependent kinase A; Provisional
      cl21453
      Location:2 → 285
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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