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    prp5 Prp19 complex WD repeat protein Prp5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 3361260, updated on 18-Sep-2024

    Summary

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    Official Symbol
    prp5
    Official Full Name
    Prp19 complex WD repeat protein Prp5
    Primary source
    PomBase:SPBP22H7.07
    Locus tag
    SPOM_SPBP22H7.07
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    cwf1
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    Genomic context

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    See prp5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (1446092..1447735)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nicotinamide riboside kinase Neighboring gene ncRNA Neighboring gene 40S ribosomal protein eS10 Neighboring gene ncRNA Neighboring gene kinetochore protein Mis15 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutants. Potashkin J, et al. Curr Genet, 1998 Sep. PMID 9745017
    2. Fission yeast Prp4p kinase regulates pre-mRNA splicing by phosphorylating a non-SR-splicing factor. Schwelnus W, et al. EMBO Rep, 2001 Jan. PMID 11252721, Free PMC Article
    3. Splicing factors facilitate RNAi-directed silencing in fission yeast. Bayne EH, et al. Science, 2008 Oct 24. PMID 18948543, Free PMC Article
    4. Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing. McDonald WH, et al. Mol Cell Biol, 1999 Aug. PMID 10409726, Free PMC Article
    5. Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. Ohi MD, et al. RNA, 2002 Jun. PMID 12088152, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mRNA cis splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Prp19 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Prp19 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    part_of post-mRNA release spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Prp19 complex WD repeat protein Prp5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1446092..1447735
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021499.3 → NP_595604.1  Prp19 complex WD repeat protein Prp5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595604.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13615
      Conserved Domains (3) summary
      COG2319
      Location:143 → 402
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:155 → 449
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:168 → 203
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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