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    ede1 EPS15 repeat-containing family actin cortical patch component protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540824, updated on 18-Sep-2024

    Summary

    Official Symbol
    ede1
    Official Full Name
    EPS15 repeat-containing family actin cortical patch component protein
    Primary source
    PomBase:SPBC800.10c
    Locus tag
    SPOM_SPBC800.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

    See ede1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (270448..274468, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene translation initiation inhibitor Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene inosine-uridine-preferring nucleoside hydrolase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables calcium ion binding ISM
    Inferred from Sequence Model
    more info
     
    Process Evidence Code Pubs
    involved_in actin cortical patch assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endosomal transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IC
    Inferred by Curator
    more info
     
    Component Evidence Code Pubs
    is_active_in actin cortical patch ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cell cortex HDA PubMed 
    is_active_in cell division site IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in growing cell tip IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    EPS15 repeat-containing family actin cortical patch component protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      270448..274468 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021019.3NP_595112.1  EPS15 repeat-containing family actin cortical patch component protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595112.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9HGL2
      Conserved Domains (4) summary
      smart00027
      Location:252345
      EH; Eps15 homology domain
      cd00052
      Location:263329
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      pfam14662
      Location:493701
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      cl12013
      Location:499704
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature