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    taf12 SAGA complex/transcription factor TFIID complex subunit A Taf12 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542785, updated on 18-Sep-2024

    Summary

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    Official Symbol
    taf12
    Official Full Name
    SAGA complex/transcription factor TFIID complex subunit A Taf12
    Primary source
    PomBase:SPAC15A10.02
    Locus tag
    SPOM_SPAC15A10.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See taf12 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3677989..3680028)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ABC family Fe transporter Atm1 Neighboring gene ncRNA Neighboring gene DNA repair protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cryo-EM reveals promoter DNA binding and conformational flexibility of the general transcription factor TFIID. Elmlund H, et al. Structure, 2009 Nov 11. PMID 19913479
    2. Anti-silencing factor Epe1 associates with SAGA to regulate transcription within heterochromatin. Bao K, et al. Genes Dev, 2019 Jan 1. PMID 30573453, Free PMC Article
    3. The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8. Helmlinger D, et al. Genes Dev, 2008 Nov 15. PMID 19056896, Free PMC Article
    4. RNA polymerase II initiation factor interactions and transcription start site selection. Li Y, et al. Science, 1994 Feb 11. PMID 8303296
    5. Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex. Helmlinger D, et al. EMBO J, 2011 Jun 3. PMID 21642955, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase II core promoter sequence-specific DNA binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables RNA polymerase II general transcription initiation factor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables TBP-class protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to transcription coactivator activity IC
    Inferred by Curator
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA polymerase II preinitiation complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of SAGA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SAGA complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription factor TFIID complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SAGA complex/transcription factor TFIID complex subunit A Taf12

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3677989..3680028
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019712.3 → NP_594289.1  SAGA complex/transcription factor TFIID complex subunit A Taf12 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594289.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13722
      Conserved Domains (1) summary
      cl22931
      Location:1 → 450
      TAF12; TATA Binding Protein (TBP) Associated Factor 12 (TAF12) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
    Nucleotide Protein
    Heading Accession and Version

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