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    sap62 U2 snRNP-associated protein Sap62 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540622, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sap62
    Official Full Name
    U2 snRNP-associated protein Sap62
    Primary source
    PomBase:SPBC21C3.05
    Locus tag
    SPOM_SPBC21C3.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See sap62 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (3805724..3806834)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ABC1 kinase family protein Neighboring gene mitochondrial 54S ribosomal protein bL34m Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene tRNA (cytosine) methyltransferase Neighboring gene ornithine transaminase Car2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Carnahan RH, et al. Eukaryot Cell, 2005 Mar. PMID 15755920, Free PMC Article
    2. The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast. Kallgren SP, et al. PLoS Genet, 2014. PMID 24874881, Free PMC Article
    3. Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing. Thakran P, et al. EMBO J, 2018 Jan 4. PMID 28947618, Free PMC Article
    4. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article
    5. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Ren L, et al. PLoS One, 2011 Feb 28. PMID 21386897, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in U2-type prespliceosome assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in mRNA cis splicing, via spliceosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in spliceosomal complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    U2 snRNP-associated protein Sap62

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3805724..3806834
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022505.3 → NP_596585.1  U2 snRNP-associated protein Sap62 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596585.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P7L8
      Conserved Domains (3) summary
      smart00451
      Location:54 → 85
      ZnF_U1; U1-like zinc finger
      COG5246
      Location:1 → 217
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      pfam16835
      Location:134 → 204
      SF3A2; Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
    Nucleotide Protein
    Heading Accession and Version

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