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    cut20 anaphase-promoting complex platform subcomplex scaffold WD repeat subunit Apc4/Cut20 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542615, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cut20
    Official Full Name
    anaphase-promoting complex platform subcomplex scaffold WD repeat subunit Apc4/Cut20
    Primary source
    PomBase:SPAC19G12.01c
    Locus tag
    SPOM_SPAC19G12.01C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    apc4; lid1; SPAPJ698.04c
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    Genomic context

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    See cut20 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003424.3 (4041809..4044624, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U2 snRNP-associated protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MutL family mismatch-repair protein Pms1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recovery from spindle checkpoint-mediated arrest requires a novel Dnt1-dependent APC/C activation mechanism. Bai S, et al. PLoS Genet, 2022 Sep. PMID 36108046, Free PMC Article
    2. Fission yeast mfr1 activates APC and coordinates meiotic nuclear division with sporulation. Blanco MA, et al. J Cell Sci, 2001 Jun. PMID 11493649
    3. Slow checkpoint activation kinetics as a safety device in anaphase. Kamenz J, et al. Curr Biol, 2014 Mar 17. PMID 24583014
    4. Study of cyclin proteolysis in anaphase-promoting complex (APC) mutant cells reveals the requirement for APC function in the final steps of the fission yeast septation initiation network. Chang L, et al. Mol Cell Biol, 2001 Oct. PMID 11533255, Free PMC Article
    5. The schizosaccharomyces pombe dim1(+) gene interacts with the anaphase-promoting complex or cyclosome (APC/C) component lid1(+) and is required for APC/C function. Berry LD, et al. Mol Cell Biol, 1999 Apr. PMID 10082519, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data suggest that Dim1p participates in pre-mRNA splicing, and in the nuclear export of lid1(+) mRNA.
      Title: Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in anaphase-promoting complex-dependent catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in anaphase-promoting complex-dependent catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic sister chromatid separation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein K11-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of anaphase-promoting complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell division site HDA PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in mitotic spindle pole body HDA PubMed 
    is_active_in nuclear periphery IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    anaphase-promoting complex platform subcomplex scaffold WD repeat subunit Apc4/Cut20

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4041809..4044624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356148.2 → NP_001342965.1  anaphase-promoting complex platform subcomplex scaffold WD repeat subunit Apc4/Cut20 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O42839, Q9P545
      Conserved Domains (3) summary
      sd00039
      Location:71 → 107
      7WD40; WD40 repeat [structural motif]
      pfam12894
      Location:33 → 122
      ANAPC4_WD40; Anaphase-promoting complex subunit 4 WD40 domain
      pfam12896
      Location:239 → 442
      ANAPC4; Anaphase-promoting complex, cyclosome, subunit 4
    Nucleotide Protein
    Heading Accession and Version

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