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    mrf1 peptide chain release factor [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541478, updated on 14-Nov-2024

    Summary

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    Official Symbol
    mrf1
    Official Full Name
    peptide chain release factor
    Primary source
    PomBase:SPAC2F7.17
    Locus tag
    SPOM_SPAC2F7.17
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mrf1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (570168..571876)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene phospholipase D Pld1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putatiRho-type GTPase-activating protein Rga8 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria. Dujeancourt L, et al. Mitochondrion, 2013 Nov. PMID 23892058, Free PMC Article
    2. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
    3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    4. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables translation release factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mitochondrial translational termination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitochondrial matrix IC
    Inferred by Curator
    more info
    		  

    General protein information

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    Preferred Names
    peptide chain release factor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      570168..571876
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018387.3 → NP_592987.1  peptide chain release factor [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592987.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09691
      Conserved Domains (3) summary
      COG0216
      Location:11 → 396
      PrfA; Protein chain release factor A [Translation, ribosomal structure and biogenesis]
      pfam00472
      Location:253 → 354
      RF-1; RF-1 domain
      pfam03462
      Location:66 → 237
      PCRF; PCRF domain
    Nucleotide Protein
    Heading Accession and Version

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