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    tps3 alpha,alpha-trehalose-phosphate synthase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542498, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tps3
    Official Full Name
    alpha,alpha-trehalose-phosphate synthase
    Primary source
    PomBase:SPACUNK4.16c
    Locus tag
    SPOM_SPACUNK4.16C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See tps3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (2877437..2880590)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene NAD-binding dehydrogenase family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein mug153 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 2',3'-cyclic-nucleotide 3'-phosphodiesterase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions. Nie M, et al. J Biol Chem, 2012 Aug 24. PMID 22730331, Free PMC Article
    2. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038
    3. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article
    4. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
    5. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in trehalose biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in trehalose biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in trehalose metabolism in response to stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    alpha,alpha-trehalose-phosphate synthase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2877437..2880590
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019389.3 → NP_593962.1  alpha,alpha-trehalose-phosphate synthase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593962.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14081
      Conserved Domains (4) summary
      cd03788
      Location:187 → 646
      GT1_TPS; Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a ...
      COG1877
      Location:663 → 944
      OtsB; Trehalose-6-phosphatase [Carbohydrate transport and metabolism]
      pfam00982
      Location:173 → 652
      Glyco_transf_20; Glycosyltransferase family 20
      pfam02358
      Location:684 → 929
      Trehalose_PPase; Trehalose-phosphatase
    Nucleotide Protein
    Heading Accession and Version

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