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    met6 homoserine O-acetyltransferase Met6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540848, updated on 18-Sep-2024

    Summary

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    Official Symbol
    met6
    Official Full Name
    homoserine O-acetyltransferase Met6
    Primary source
    PomBase:SPBC56F2.11
    Locus tag
    SPOM_SPBC56F2.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See met6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (4088686..4091248, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene acetohydroxyacid reductoisomerase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dolichyl-phosphate beta-glucosyltransferase Alg5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Methionine induces sexual development in the fission yeast Schizosaccharomyces pombe via an ste11-dependent signalling pathway. Schweingruber AM, et al. J Bacteriol, 1998 Dec. PMID 9829945, Free PMC Article
    2. Catalytic mechanism of fungal homoserine transacetylase. Nazi I, et al. Biochemistry, 2005 Oct 18. PMID 16216079
    3. Methionine sulphoxide reductases revisited: free methionine as a primary target of H₂O₂stress in auxotrophic fission yeast. García-Santamarina S, et al. Mol Microbiol, 2013 Dec. PMID 24118096
    4. Six new amino acid-auxotrophic markers for targeted gene integration and disruption in fission yeast. Ma Y, et al. Curr Genet, 2007 Aug. PMID 17622533
    5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables homoserine O-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables homoserine O-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 'de novo' L-methionine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in homoserine metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in methionine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in methionine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    homoserine O-acetyltransferase Met6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4088686..4091248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022631.3 → NP_596706.2  homoserine O-acetyltransferase Met6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596706.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60062
      Conserved Domains (2) summary
      TIGR01392
      Location:37 → 451
      homoserO_Ac_trn; homoserine O-acetyltransferase
      cl21494
      Location:40 → 449
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version

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