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    cdc27 DNA polymerase delta subunit Cdc27 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539627, updated on 14-Nov-2024

    Summary

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    Official Symbol
    cdc27
    Official Full Name
    DNA polymerase delta subunit Cdc27
    Primary source
    PomBase:SPBC1734.02c
    Locus tag
    SPOM_SPBC1734.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPBC337.18c
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    Genomic context

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    See cdc27 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003423.3 (1061718..1063424, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pre-rRNA processing protein Esf1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dihydropteroate synthase Neighboring gene ncRNA Neighboring gene mannan polymerase I complex subunit Anp1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A key role for replication factor C in DNA replication checkpoint function in fission yeast. Reynolds N, et al. Nucleic Acids Res, 1999 Jan 15. PMID 9862966, Free PMC Article
    2. Functional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis. Sanchez Garcia J, et al. BMC Mol Biol, 2009 Aug 17. PMID 19686603, Free PMC Article
    3. The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27. MacNeill SA, et al. EMBO J, 1996 Sep 2. PMID 8887553, Free PMC Article
    4. DNA polymerase delta isolated from Schizosaccharomyces pombe contains five subunits. Zuo S, et al. Proc Natl Acad Sci U S A, 1997 Oct 14. PMID 9326594, Free PMC Article
    5. Structure and activity associated with multiple forms of Schizosaccharomyces pombe DNA polymerase delta. Zuo S, et al. J Biol Chem, 2000 Feb 18. PMID 10671561

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to 3'-5' exonuclease activity IC
    Inferred by Curator
    more info
    		 PubMed 
    contributes_to DNA-directed DNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to DNA-directed DNA polymerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA strand elongation involved in DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA strand elongation involved in mitotic DNA replication IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in DNA synthesis involved in UV-damage excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA synthesis involved in UV-damage excision repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitotic DNA replication lagging strand elongation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mitotic DNA replication leading strand elongation NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in nucleotide-excision repair, DNA gap filling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    part_of delta DNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of delta DNA polymerase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    DNA polymerase delta subunit Cdc27

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1061718..1063424 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021326.3 → NP_595419.1  DNA polymerase delta subunit Cdc27 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595419.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P30261
      Conserved Domains (1) summary
      pfam09507
      Location:157 → 372
      CDC27; DNA polymerase subunit Cdc27
    Nucleotide Protein
    Heading Accession and Version

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