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    alp31 tubulin-specific chaperone cofactor A Alp31 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543341, updated on 18-Sep-2024

    Summary

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    Official Symbol
    alp31
    Official Full Name
    tubulin-specific chaperone cofactor A Alp31
    Primary source
    PomBase:SPAC8E11.07c
    Locus tag
    SPOM_SPAC8E11.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See alp31 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (3377106..3378081)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene palmitoyl-(protein) hydrolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cofactor-dependent pathways for alpha- and beta-tubulins in microtubule biogenesis are functionally different in fission yeast. Radcliffe PA, et al. Genetics, 2000 Sep. PMID 10978278, Free PMC Article
    2. Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B. Buttrick GJ, et al. Mol Biol Cell, 2011 Dec. PMID 21965289, Free PMC Article
    3. Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. Beltrao P, et al. PLoS Biol, 2009 Jun 16. PMID 19547744, Free PMC Article
    4. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables beta-tubulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein folding chaperone IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in post-chaperonin tubulin folding pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tubulin complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    tubulin-specific chaperone cofactor A Alp31

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3377106..3378081
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019586.3 → NP_594162.1  tubulin-specific chaperone cofactor A Alp31 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594162.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9Y703
      Conserved Domains (1) summary
      pfam02970
      Location:8 → 95
      TBCA; Tubulin binding cofactor A
    Nucleotide Protein
    Heading Accession and Version

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