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    ssb3 DNA replication factor A subunit Ssb3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538775, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ssb3
    Official Full Name
    DNA replication factor A subunit Ssb3
    Primary source
    PomBase:SPCC23B6.05c
    Locus tag
    SPOM_SPCC23B6.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    rpa3
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    Genomic context

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    See ssb3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003421.2 (1281886..1282401, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ATM checkpoint kinase Neighboring gene ncRNA Neighboring gene sec14 family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 3' ssRNA-specific 3'-to-5' exonuclease

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification, gene cloning, and reconstitution of the heterotrimeric single-stranded DNA-binding protein from Schizosaccharomyces pombe. Ishiai M, et al. J Biol Chem, 1996 Aug 23. PMID 8702843
    2. Fission yeast Taz1 and RPA are synergistically required to prevent rapid telomere loss. Kibe T, et al. Mol Biol Cell, 2007 Jun. PMID 17429064, Free PMC Article
    3. The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks. Teixeira-Silva A, et al. Nat Commun, 2017 Dec 7. PMID 29215009, Free PMC Article
    4. Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast. Tay Z, et al. PLoS One, 2013. PMID 23365689, Free PMC Article
    5. Replication fork collapse and genome instability in a deoxycytidylate deaminase mutant. Sánchez A, et al. Mol Cell Biol, 2012 Nov. PMID 22927644, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables damaged DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA replication, synthesis of primer ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in base-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mismatch repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic DNA replication ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in nucleotide-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in telomere maintenance NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    part_of DNA replication factor A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of DNA replication factor A complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromosome, telomeric repeat region ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in site of double-strand break IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in site of double-strand break IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA replication factor A subunit Ssb3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1281886..1282401 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023118.3 → NP_588128.1  DNA replication factor A subunit Ssb3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588128.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q92374
      Conserved Domains (1) summary
      pfam08661
      Location:1 → 102
      Rep_fac-A_3; Replication factor A protein 3
    Nucleotide Protein
    Heading Accession and Version

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