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    rpb8 DNA-directed RNA polymerase subunit Rpb8 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539794, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rpb8
    Official Full Name
    DNA-directed RNA polymerase subunit Rpb8
    Primary source
    PomBase:SPBC14C8.12
    Locus tag
    SPOM_SPBC14C8.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See rpb8 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (2223646..2224720)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene mitochondrial 54S ribosomal protein bL28m Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SRR1 family protein, DNA-repair associated protein, Srr1, conflicting annotations across species Neighboring gene rRNA processing protein Pol5 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Structural-functional characteristics of the Schizosaccharomyces pombe rpb8+ gene, coding the subunit of RNA polymerase I-III, specific only for eukaryotes]. Shpakovskiĭ GV, et al. Bioorg Khim, 1998 Feb. PMID 10335407
    2. The Rpb4 subunit of fission yeast Schizosaccharomyces pombe RNA polymerase II is essential for cell viability and similar in structure to the corresponding subunits of higher eukaryotes. Sakurai H, et al. Mol Cell Biol, 1999 Nov. PMID 10523639, Free PMC Article
    3. Location of subunit-subunit contact sites on RNA polymerase II subunit 3 from the fission yeast Schizosaccharomyces pombe. Yasui K, et al. Biochemistry, 1998 Apr 21. PMID 9548938
    4. Gene organization and protein sequence of the small subunits of Schizosaccharomyces pombe RNA polymerase II. Sakurai H, et al. Gene, 1997 Sep 1. PMID 9322754
    5. RNA polymerase II subunits 2, 3, and 11 form a core subassembly with DNA binding activity. Kimura M, et al. J Biol Chem, 1997 Oct 10. PMID 9325316

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to RNA polymerase I activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase II activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase III activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase II TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase III TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase I EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase I complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase II, core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase II, core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase II, holoenzyme EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase III complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase subunit Rpb8

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2223646..2224720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021823.3 → NP_595915.1  DNA-directed RNA polymerase subunit Rpb8 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595915.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13459, O13460, Q92399
      Conserved Domains (1) summary
      smart00658
      Location:3 → 125
      RPOL8c; RNA polymerase subunit 8
    Nucleotide Protein
    Heading Accession and Version

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