suc22 ribonucleotide reductase small subunit Suc22 [Schizosaccharomyces pombe (fission yeast)] - Gene

Summary

Official Symbol: suc22
Official Full Name: ribonucleotide reductase small subunit Suc22
Primary source: PomBase:SPBC25D12.04
Locus tag: SPOM_SPBC25D12.04
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Schizosaccharomyces pombe (strain: 972h-)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Chromosome II - NC_003423.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Spd1 inhibits ribonucleotide reductase (RNR) activity by anchoring the small RNR subunit Suc22 in the nucleus.
Title: Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms.
Spd1p inhibits fission yeast ribonucleotide reductase (RNR) activity by binding to Cdc22p, which is the large subunit of RNR, and not to Suc22p, which is the small subunit of RNR.
Title: The Schizosaccharomyces pombe replication inhibitor Spd1 regulates ribonucleotide reductase activity and dNTPs by binding to the large Cdc22 subunit.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to CDP reductase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in CDP metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in dCDP biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in purine deoxyribonucleoside triphosphate biosynthetic process	IC Inferred by Curator more info
involved_in purine nucleoside metabolic process	IC Inferred by Curator more info
involved_in pyrimidine deoxyribonucleoside triphosphate biosynthetic process	IC Inferred by Curator more info
involved_in pyrimidine nucleoside metabolic process	IC Inferred by Curator more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytosol	HDA more info	PubMed
is_active_in nucleus	HDA more info	PubMed
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed
part_of ribonucleoside-diphosphate reductase complex	IPI Inferred from Physical Interaction more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain