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    hmo1 upstream binding transcription factor, RNA polymerase I specific, Hmo1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540337, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hmo1
    Official Full Name
    upstream binding transcription factor, RNA polymerase I specific, Hmo1
    Primary source
    PomBase:SPBC28F2.11
    Locus tag
    SPOM_SPBC28F2.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See hmo1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (1589285..1590907)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SAGA complex subunit Ngg1/Ada3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA-directed RNA polymerase II complex large subunit Rpb1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure-function analysis of Hmo1 unveils an ancestral organization of HMG-Box factors involved in ribosomal DNA transcription from yeast to human. Albert B, et al. Nucleic Acids Res, 2013 Dec. PMID 24021628, Free PMC Article
    2. Clr4 specificity and catalytic activity beyond H3K9 methylation. Kusevic D, et al. Biochimie, 2017 Apr. PMID 28143796
    3. Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast. Koch A, et al. Sci Signal, 2011 Jun 28. PMID 21712547
    4. A novel histone deacetylase complex in the control of transcription and genome stability. Zilio N, et al. Mol Cell Biol, 2014 Sep 15. PMID 25002536, Free PMC Article
    5. Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Dixon SJ, et al. Proc Natl Acad Sci U S A, 2008 Oct 28. PMID 18931302, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables RNA polymerase I general transcription initiation factor activity NAS
    Non-traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase I promoter ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    upstream binding transcription factor, RNA polymerase I specific, Hmo1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1589285..1590907
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021567.3 → NP_595672.1  upstream binding transcription factor, RNA polymerase I specific, Hmo1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595672.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9USU7
      Conserved Domains (2) summary
      COG5648
      Location:108 → 251
      NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
      cd01390
      Location:117 → 184
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    Nucleotide Protein
    Heading Accession and Version

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