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    Fzd10 frizzled class receptor 10 [ Mus musculus (house mouse) ]

    Gene ID: 93897, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fzd10provided by MGI
    Official Full Name
    frizzled class receptor 10provided by MGI
    Primary source
    MGI:MGI:2136761
    See related
    Ensembl:ENSMUSG00000081683 AllianceGenome:MGI:2136761
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fz-10
    Summary
    Enables Wnt-protein binding activity. Acts upstream of or within Wnt signaling pathway. Predicted to be located in cell surface; cytoplasm; and nucleoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human FZD10 (frizzled class receptor 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Fzd10 in Genome Data Viewer
    Location:
    5 G1.3; 5 67.67 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (128678170..128681157)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (128601106..128604093)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38612 Neighboring gene frizzled class receptor 10, opposite strand Neighboring gene STARR-seq mESC enhancer starr_14425 Neighboring gene STARR-seq mESC enhancer starr_14426 Neighboring gene predicted gene, 33931 Neighboring gene STARR-seq mESC enhancer starr_14427 Neighboring gene predicted gene, 33995

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables Wnt receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables Wnt receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables Wnt-protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables Wnt-protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within Wnt signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in non-canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in non-canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in non-canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of JNK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of JNK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of regulation of actin cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    frizzled-10
    Names
    frizzled homolog 10

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175284.3NP_780493.1  frizzled-10 precursor

      See identical proteins and their annotated locations for NP_780493.1

      Status: PROVISIONAL

      Source sequence(s)
      AY509002
      Consensus CDS
      CCDS51652.1
      UniProtKB/Swiss-Prot
      Q8BKG4
      UniProtKB/TrEMBL
      Q149J3, Q71S95
      Related
      ENSMUSP00000114114.3, ENSMUST00000117102.4
      Conserved Domains (2) summary
      pfam01534
      Location:219536
      Frizzled; Frizzled/Smoothened family membrane region
      cl02447
      Location:31157
      CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      128678170..128681157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)