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    NLGN1 neuroligin 1 [ Homo sapiens (human) ]

    Gene ID: 22871, updated on 3-Dec-2024

    Summary

    Official Symbol
    NLGN1provided by HGNC
    Official Full Name
    neuroligin 1provided by HGNC
    Primary source
    HGNC:HGNC:14291
    See related
    Ensembl:ENSG00000169760 MIM:600568; AllianceGenome:HGNC:14291
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NL1; NLG1
    Summary
    This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in brain (RPKM 1.7), testis (RPKM 0.4) and 11 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See NLGN1 in Genome Data Viewer
    Location:
    3q26.31
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (173395952..174294372)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (176181719..177081314)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (173113742..174012162)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374224 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:172963126-172963695 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:172971223-172971761 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:173004473-173004973 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:173070760-173071467 Neighboring gene uncharacterized LOC124909458 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14900 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14901 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:173113803-173114302 Neighboring gene NANOG hESC enhancer GRCh37_chr3:173128110-173128611 Neighboring gene transmembrane protein 229B-like Neighboring gene uncharacterized LOC105374225 Neighboring gene NANOG hESC enhancer GRCh37_chr3:173523180-173523681 Neighboring gene Sharpr-MPRA regulatory region 253 Neighboring gene NLGN1 antisense RNA 1 Neighboring gene RN7SK pseudogene 234 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:173929552-173930052 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:173948692-173949418 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:173949419-173950143 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:173950144-173950869 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr3:173950870-173951594 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:173982710-173983249 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:173983250-173983788 Neighboring gene ANAPC15 pseudogene 2 Neighboring gene ribosomal protein L8 pseudogene 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Autism, susceptibility to, 20
    MedGen: C5394226 OMIM: 618830 GeneReviews: Not available
    Compare labs

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated 2016-03-25)

    ClinGen Genome Curation Page
    Haploinsufficency

    No evidence available (Last evaluated 2016-03-25)

    ClinGen Genome Curation PagePubMed

    EBI GWAS Catalog

    Description
    Genome-wide association study of chronic periodontitis in a general German population.
    EBI GWAS Catalog
    Genome-wide association study of major recurrent depression in the U.K. population.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1070, MGC45115

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables PDZ domain binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables amyloid-beta binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables cell adhesion molecule binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables identical protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables neurexin family protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables neurexin family protein binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables scaffold protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables signaling receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in AMPA glutamate receptor clustering ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in NMDA glutamate receptor clustering ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in cellular response to calcium ion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cytoskeletal matrix organization at active zone ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in establishment of protein localization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in excitatory synapse assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in modulation of chemical synaptic transmission ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of dendritic spine morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in nervous system development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neurexin clustering involved in presynaptic membrane assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neuron cell-cell adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neuron cell-cell adhesion NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in neuron cell-cell adhesion TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in neuron projection arborization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neuron projection development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neuron projection morphogenesis NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in neuronal signal transduction TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of circadian sleep/wake cycle, wakefulness ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of dendritic spine development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of dendritic spine development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of excitatory postsynaptic potential IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of excitatory postsynaptic potential ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of filopodium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of intracellular signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of neuromuscular synaptic transmission NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of ruffle assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within positive regulation of synapse assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of synapse assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of synaptic transmission, GABAergic ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of synaptic transmission, GABAergic NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of synaptic transmission, glutamatergic ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of synaptic transmission, glutamatergic NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of synaptic vesicle endocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of synaptic vesicle exocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in postsynaptic density protein 95 clustering ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in postsynaptic membrane assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in presynapse assembly TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in presynaptic membrane assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein localization to synapse ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein targeting ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in receptor localization to synapse ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of AMPA receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of NMDA receptor activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of NMDA receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of neuron differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in rhythmic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in synapse assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in synaptic vesicle clustering ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in synaptic vesicle targeting ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in terminal button organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in GABA-ergic synapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in asymmetric, glutamatergic, excitatory synapse TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in cell surface ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in dendrite ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in dendritic spine ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in excitatory synapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in filopodium tip ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in glutamatergic synapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in neuromuscular junction NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    located_in postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in postsynaptic density TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in postsynaptic membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    is_active_in postsynaptic specialization membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in postsynaptic specialization membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein complex involved in cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein complex involved in cell-cell adhesion NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of receptor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in synapse ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in synaptic cleft IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_046919.2 RefSeqGene

      Range
      6846..903474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001365923.2NP_001352852.1  neuroligin-1 isoform 1 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    2. NM_001365924.2NP_001352853.1  neuroligin-1 isoform 2 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      Consensus CDS
      CCDS93427.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      UniProtKB/TrEMBL
      A0A8Q3SHM6
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    3. NM_001365925.2NP_001352854.1  neuroligin-1 isoform 2 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      Consensus CDS
      CCDS93427.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      UniProtKB/TrEMBL
      A0A8Q3SHM6
      Related
      ENSP00000511841.1, ENST00000695368.1
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    4. NM_001365926.2NP_001352855.1  neuroligin-1 isoform 2 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      Consensus CDS
      CCDS93427.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      UniProtKB/TrEMBL
      A0A8Q3SHM6
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    5. NM_001365927.2NP_001352856.1  neuroligin-1 isoform 1 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC092923, AC092967
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Related
      ENSP00000410374.2, ENST00000415045.2
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    6. NM_001365928.2NP_001352857.1  neuroligin-1 isoform 2 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC092923, AC092967
      Consensus CDS
      CCDS93427.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      UniProtKB/TrEMBL
      A0A8Q3SHM6
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    7. NM_001365929.2NP_001352858.1  neuroligin-1 isoform 3 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      Consensus CDS
      CCDS3222.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52606
      COesterase; Carboxylesterase family
    8. NM_001365930.2NP_001352859.1  neuroligin-1 isoform 3 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      Consensus CDS
      CCDS3222.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52606
      COesterase; Carboxylesterase family
    9. NM_001365931.2NP_001352860.1  neuroligin-1 isoform 3 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      Consensus CDS
      CCDS3222.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52606
      COesterase; Carboxylesterase family
    10. NM_001365932.2NP_001352861.1  neuroligin-1 isoform 3 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      Consensus CDS
      CCDS3222.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52606
      COesterase; Carboxylesterase family
    11. NM_001365933.2NP_001352862.1  neuroligin-1 isoform 3 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC092923, AC092967
      Consensus CDS
      CCDS3222.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Related
      ENSP00000354541.4, ENST00000361589.8
      Conserved Domains (1) summary
      pfam00135
      Location:52606
      COesterase; Carboxylesterase family
    12. NM_001365934.2NP_001352863.1  neuroligin-1 isoform 4 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC092923, AC092967
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52597
      COesterase; Carboxylesterase family
    13. NM_001365935.2NP_001352864.1  neuroligin-1 isoform 4 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52597
      COesterase; Carboxylesterase family
    14. NM_001365936.2NP_001352865.1  neuroligin-1 isoform 4 precursor

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, AC092923, AC092967
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52597
      COesterase; Carboxylesterase family
    15. NM_014932.5NP_055747.1  neuroligin-1 isoform 3 precursor

      See identical proteins and their annotated locations for NP_055747.1

      Status: REVIEWED

      Source sequence(s)
      AC008120, AC018456, BC032555, DA310134
      Consensus CDS
      CCDS3222.1
      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Related
      ENSP00000392500.1, ENST00000457714.5
      Conserved Domains (1) summary
      pfam00135
      Location:52606
      COesterase; Carboxylesterase family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

      Range
      173395952..174294372
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017005893.2XP_016861382.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    2. XM_047447706.1XP_047303662.1  neuroligin-1 isoform X2

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    3. XM_017005896.2XP_016861385.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    4. XM_047447712.1XP_047303668.1  neuroligin-1 isoform X5

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    5. XM_017005888.2XP_016861377.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    6. XM_047447709.1XP_047303665.1  neuroligin-1 isoform X5

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    7. XM_047447708.1XP_047303664.1  neuroligin-1 isoform X4

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    8. XM_017005902.2XP_016861391.1  neuroligin-1 isoform X5

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52597
      COesterase; Carboxylesterase family
    9. XM_047447707.1XP_047303663.1  neuroligin-1 isoform X3

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    10. XM_047447702.1XP_047303658.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    11. XM_017005900.2XP_016861389.1  neuroligin-1 isoform X4

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52606
      COesterase; Carboxylesterase family
    12. XM_047447710.1XP_047303666.1  neuroligin-1 isoform X5

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    13. XM_047447704.1XP_047303660.1  neuroligin-1 isoform X3

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    14. XM_047447701.1XP_047303657.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    15. XM_047447703.1XP_047303659.1  neuroligin-1 isoform X2

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    16. XM_017005895.3XP_016861384.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
      Conserved Domains (1) summary
      pfam00135
      Location:52626
      COesterase; Carboxylesterase family
    17. XM_047447705.1XP_047303661.1  neuroligin-1 isoform X2

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    18. XM_005247237.4XP_005247294.1  neuroligin-1 isoform X6

      Conserved Domains (2) summary
      COG0657
      Location:14112
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
      pfam00135
      Location:16454
      COesterase; Carboxylesterase family
    19. XM_047447713.1XP_047303669.1  neuroligin-1 isoform X7

    20. XM_047447714.1XP_047303670.1  neuroligin-1 isoform X7

    21. XM_011512553.3XP_011510855.1  neuroligin-1 isoform X7

      See identical proteins and their annotated locations for XP_011510855.1

      Conserved Domains (1) summary
      cl21494
      Location:2292
      Abhydrolase; alpha/beta hydrolases

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060927.1 Alternate T2T-CHM13v2.0

      Range
      176181719..177081314
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054345678.1XP_054201653.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    2. XM_054345684.1XP_054201659.1  neuroligin-1 isoform X2

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    3. XM_054345680.1XP_054201655.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    4. XM_054345691.1XP_054201666.1  neuroligin-1 isoform X5

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    5. XM_054345675.1XP_054201650.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    6. XM_054345688.1XP_054201663.1  neuroligin-1 isoform X5

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    7. XM_054345687.1XP_054201662.1  neuroligin-1 isoform X4

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    8. XM_054345689.1XP_054201664.1  neuroligin-1 isoform X5

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    9. XM_054345685.1XP_054201660.1  neuroligin-1 isoform X3

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    10. XM_054345677.1XP_054201652.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    11. XM_054345686.1XP_054201661.1  neuroligin-1 isoform X4

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    12. XM_054345690.1XP_054201665.1  neuroligin-1 isoform X5

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    13. XM_054345682.1XP_054201657.1  neuroligin-1 isoform X3

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    14. XM_054345676.1XP_054201651.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    15. XM_054345681.1XP_054201656.1  neuroligin-1 isoform X2

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    16. XM_054345679.1XP_054201654.1  neuroligin-1 isoform X1

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    17. XM_054345683.1XP_054201658.1  neuroligin-1 isoform X2

      UniProtKB/Swiss-Prot
      D2X2H5, Q8N2Q7, Q9UPT2
    18. XM_054345692.1XP_054201667.1  neuroligin-1 isoform X6

    19. XM_054345693.1XP_054201668.1  neuroligin-1 isoform X7