Eif1ad eukaryotic translation initiation factor 1A domain containing [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Eif1adprovided by MGI
Official Full Name: eukaryotic translation initiation factor 1A domain containingprovided by MGI
Primary source: MGI:MGI:1917110
See related: Ensembl:ENSMUSG00000024841 AllianceGenome:MGI:1917110
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Eif1ad1; 2010003J03Rik
Summary: Predicted to enable RNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including adrenal gland; brain; genitourinary system; gut; and respiratory system. Orthologous to human EIF1AD (eukaryotic translation initiation factor 1A domain containing). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 20.2), thymus adult (RPKM 14.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 19 A; 19 4.31 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (5416841..5421546)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (5366813..5371518)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: probable RNA-binding protein EIF1AD

Names: eukaryotic translation initiation factor 1A domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_027236.2 → NP_081512.1 probable RNA-binding protein EIF1AD

See identical proteins and their annotated locations for NP_081512.1

Status: PROVISIONAL

Source sequence(s)

AC122861

Consensus CDS

CCDS29459.1

UniProtKB/Swiss-Prot

Q3THJ3, Q8K1C2, Q9D8F9

Related

ENSMUSP00000025759.8, ENSMUST00000025759.9

Conserved Domains (1) summary

cd05792
Location:25 → 102

S1_eIF1AD_like; eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found in a wide ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000085.7 Reference GRCm39 C57BL/6J

Range

5416841..5421546

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030251073.1 → XP_030106933.1 probable RNA-binding protein EIF1AD isoform X1

UniProtKB/Swiss-Prot

Q3THJ3, Q8K1C2, Q9D8F9

Conserved Domains (1) summary

cd05792
Location:25 → 102

S1_eIF1AD_like; eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found in a wide ...