U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PLCD1 phospholipase C delta 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 281986, updated on 30-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    PLCD1provided by VGNC
    Official Full Name
    phospholipase C delta 1provided by VGNC
    Primary source
    VGNC:VGNC:32984
    See related
    BGD:BT10287; EnsemblRapid:ENSBTAG00070022448
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PLCD1 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (11459790..11481187, complement)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene CTD small phosphatase like Neighboring gene microRNA mir-26a-1 Neighboring gene microRNA mir-26c Neighboring gene villin like Neighboring gene DLEC1 cilia and flagella associated protein Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene acetyl-CoA acyltransferase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Cloning and sequence of multiple forms of phospholipase C. Suh PG, et al. Cell, 1988 Jul 15. PMID 3390863
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in release of sequestered calcium ion into cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
    Names
    PLC-III
    PLC-delta-1
    phosphoinositide phospholipase C
    phosphoinositide phospholipase C-delta-1
    phospholipase C-III
    NP_001075045.1
    XP_005222429.1
    XP_059735439.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081576.1 → NP_001075045.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

      See identical proteins and their annotated locations for NP_001075045.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133304
      UniProtKB/Swiss-Prot
      A2VDM2, P10895
      UniProtKB/TrEMBL
      A0A3Q1LGP3
      Related
      ENSBTAP00070030233.1, ENSBTAT00070050602.1
      Conserved Domains (4) summary
      cd00275
      Location:628 → 755
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08593
      Location:295 → 596
      PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
      cd13363
      Location:22 → 139
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16217
      Location:144 → 283
      EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      11459790..11481187 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005222372.4 → XP_005222429.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

      See identical proteins and their annotated locations for XP_005222429.1

      UniProtKB/TrEMBL
      A0A3Q1LGP3, A0AAA9T888
      Related
      ENSBTAP00070030203.1, ENSBTAT00070050548.1
      Conserved Domains (4) summary
      cd00275
      Location:653 → 780
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08593
      Location:320 → 621
      PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
      cd13363
      Location:47 → 164
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16217
      Location:169 → 308
      EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)

    2. XM_059879456.1 → XP_059735439.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LGP3
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P10895.2 GenPept UniProtKB/Swiss-Prot:P10895

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.