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    IGLV4-60 immunoglobulin lambda variable 4-60 [ Homo sapiens (human) ]

    Gene ID: 28785, updated on 4-Jan-2025

    Summary

    Official Symbol
    IGLV4-60provided by HGNC
    Official Full Name
    immunoglobulin lambda variable 4-60provided by HGNC
    Primary source
    HGNC:HGNC:5920
    See related
    Ensembl:ENSG00000211639 IMGT/GENE-DB:IGLV4-60; AllianceGenome:HGNC:5920
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    V5-4; IGLV460
    Summary
    Predicted to be involved in immune response. Predicted to be located in extracellular region and plasma membrane. Predicted to be part of immunoglobulin complex. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See IGLV4-60 in Genome Data Viewer
    Location:
    22q11.22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (22162198..22162681)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (22575734..22576216)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (22516591..22517074)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene NAD kinase 2, mitochondrial pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18720 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13522 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:22482353-22482868 Neighboring gene immunoglobulin lambda locus Neighboring gene ABHD17A pseudogene 5 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:22510059-22510201 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18721 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:22518113-22518300 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18722 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18723 Neighboring gene immunoglobulin lambda variable (IV)-59 (pseudogene) Neighboring gene suppressor of cytokine signaling 2 pseudogene 2

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in adaptive immune response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    part_of immunoglobulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_000002.1 

      Range
      140580..141063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      22162198..22162681
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      22575734..22576216
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)