Ufsp1 UFM1-specific peptidase 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ufsp1provided by MGI
Official Full Name: UFM1-specific peptidase 1provided by MGI
Primary source: MGI:MGI:1917490
See related: Ensembl:ENSMUSG00000051502 AllianceGenome:MGI:1917490
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: D5Ertd655e; 2700038N03Rik
Summary: Enables deUFMylase activity. Predicted to be involved in protein maturation. Predicted to be active in cytosol. Is expressed in several structures, including diaphragm; limb segment; nervous system; skeletal musculature; and thymus primordium. Orthologous to human UFSP1 (UFM1 specific peptidase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human all
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Genomic context

Location:: 5 G2; 5 76.33 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (137292931..137293926)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (137294669..137295664)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

loop between beta3 and alpha2 in addition to the C-terminal region of Ufm1 plays a role in binding to UfSP1
Title: Structural basis for Ufm1 processing by UfSP1.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

2700038N03Rik (e-PCR), detects polymorphism
- UniSTS:167459

Ache (e-PCR), detects polymorphism
- UniSTS:141003

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables cysteine-type peptidase activity	ISO Inferred from Sequence Orthology more info
enables deUFMylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables deUFMylase activity	IDA Inferred from Direct Assay more info	PubMed
enables deUFMylase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables deUFMylase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in protein maturation	ISO Inferred from Sequence Orthology more info
involved_in protein maturation	ISS Inferred from Sequence or Structural Similarity more info
involved_in proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in cytosol	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: ufm1-specific protease 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.