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    Eif3m eukaryotic translation initiation factor 3, subunit M [ Mus musculus (house mouse) ]

    Gene ID: 98221, updated on 9-Dec-2024

    Summary

    Official Symbol
    Eif3mprovided by MGI
    Official Full Name
    eukaryotic translation initiation factor 3, subunit Mprovided by MGI
    Primary source
    MGI:MGI:1351744
    See related
    Ensembl:ENSMUSG00000027170 AllianceGenome:MGI:1351744
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ga17; Pcid1; Tango7
    Summary
    Enables translation initiation factor binding activity. Acts upstream of or within translation. Part of eukaryotic translation initiation factor 3 complex, eIF3m. Is expressed in several structures, including central nervous system; liver; metanephros; thymus primordium; and upper jaw tooth. Orthologous to human EIF3M (eukaryotic translation initiation factor 3 subunit M). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 56.9), placenta adult (RPKM 55.1) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Eif3m in Genome Data Viewer
    Location:
    2 E2; 2 55.06 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (104830001..104847372, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (104999656..105017027, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene TAR DNA binding protein pseudogene Neighboring gene proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) Neighboring gene STARR-positive B cell enhancer ABC_E7844 Neighboring gene STARR-seq mESC enhancer starr_05298 Neighboring gene STARR-positive B cell enhancer mm9_chr2:104728128-104728428 Neighboring gene coiled-coil domain containing 73 Neighboring gene STARR-positive B cell enhancer mm9_chr2:104828551-104828851 Neighboring gene predicted gene, 38521 Neighboring gene NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC118449

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to translation initiation factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation initiation factor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in formation of cytoplasmic translation initiation complex IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 3 subunit M
    Names
    PCI domain containing 1 (herpesvirus entry mediator)
    PCI domain-containing protein 1
    dendritic cell protein GA17
    NP_663355.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145380.2NP_663355.1  eukaryotic translation initiation factor 3 subunit M

      See identical proteins and their annotated locations for NP_663355.1

      Status: PROVISIONAL

      Source sequence(s)
      AL606494
      Consensus CDS
      CCDS16495.1
      UniProtKB/Swiss-Prot
      Q3TI04, Q5EBI5, Q99JX4
      Related
      ENSMUSP00000028592.6, ENSMUST00000028592.12
      Conserved Domains (1) summary
      smart00088
      Location:269357
      PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      104830001..104847372 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)