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    Sdr9c7 4short chain dehydrogenase/reductase family 9C, member 7 [ Mus musculus (house mouse) ]

    Gene ID: 70061, updated on 27-Nov-2024

    Summary

    Official Symbol
    Sdr9c7provided by MGI
    Official Full Name
    4short chain dehydrogenase/reductase family 9C, member 7provided by MGI
    Primary source
    MGI:MGI:1917311
    See related
    Ensembl:ENSMUSG00000040127 AllianceGenome:MGI:1917311
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rdhs; Sdro; Rdh20; SDR-O; 1810054F20Rik
    Summary
    Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity. Predicted to be involved in retinol metabolic process and steroid metabolic process. Predicted to be located in cytoplasm. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Used to study autosomal recessive congenital ichthyosis 13. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 13. Orthologous to human SDR9C7 (short chain dehydrogenase/reductase family 9C member 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in liver adult (RPKM 5.3), stomach adult (RPKM 2.3) and 2 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sdr9c7 in Genome Data Viewer
    Location:
    10 D3; 10 76.39 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (127734404..127747630)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (127898535..127911761)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RDH16 family member 2 Neighboring gene predicted gene, 31091 Neighboring gene STARR-seq mESC enhancer starr_28247 Neighboring gene retinol dehydrogenase 7 Neighboring gene STARR-seq mESC enhancer starr_28249 Neighboring gene STARR-seq mESC enhancer starr_28250 Neighboring gene predicted gene, 40804 Neighboring gene predicted gene, 40805 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:127382698-127382807 Neighboring gene ecotropic viral integration site 5 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables all-trans-retinol dehydrogenase (NAD+) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables all-trans-retinol dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables all-trans-retinol dehydrogenase (NAD+) activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in retinol metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in steroid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    short-chain dehydrogenase/reductase family 9C member 7
    Names
    RDH-S
    orphan short chain dehydrogenase/reductase
    retinol dehydrogenase 20
    NP_081577.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027301.3NP_081577.1  short-chain dehydrogenase/reductase family 9C member 7

      See identical proteins and their annotated locations for NP_081577.1

      Status: VALIDATED

      Source sequence(s)
      BC064820
      Consensus CDS
      CCDS24256.1
      UniProtKB/Swiss-Prot
      Q8K3P0
      Related
      ENSMUSP00000036628.8, ENSMUST00000047134.8
      Conserved Domains (2) summary
      cd09805
      Location:26302
      type2_17beta_HSD-like_SDR_c; human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs
      pfam00106
      Location:26207
      adh_short; short chain dehydrogenase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      127734404..127747630
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)