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    4930486L24Rik RIKEN cDNA 4930486L24 gene [ Mus musculus (house mouse) ]

    Gene ID: 214639, updated on 9-Dec-2024

    Summary

    Official Symbol
    4930486L24Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 4930486L24 geneprovided by MGI
    Primary source
    MGI:MGI:1922258
    See related
    Ensembl:ENSMUSG00000050345 AllianceGenome:MGI:1922258
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable cysteine-type endopeptidase activator activity involved in apoptotic process and cysteine-type endopeptidase activity. Predicted to be involved in immune response; positive regulation of apoptotic signaling pathway; and proteolysis involved in protein catabolic process. Predicted to be located in cell junction. Predicted to be active in extracellular space and lysosome. Is expressed in adrenal gland. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in placenta adult (RPKM 18.7) and adrenal adult (RPKM 2.2) See more
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    Genomic context

    See 4930486L24Rik in Genome Data Viewer
    Location:
    13 B2; 13 32.53 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (60990426..61012230, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (60842612..60864416, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene cDNA sequence BC051665 Neighboring gene cathepsin L-like 3 Neighboring gene STARR-seq mESC enhancer starr_34742 Neighboring gene STARR-seq mESC enhancer starr_34743 Neighboring gene cytotoxic T lymphocyte-associated protein 2 beta Neighboring gene trophoblast specific protein beta

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proteolysis involved in protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178098.2NP_835199.1  testin-2 precursor

      See identical proteins and their annotated locations for NP_835199.1

      Status: PROVISIONAL

      Source sequence(s)
      AY146988
      Consensus CDS
      CCDS26583.1
      UniProtKB/Swiss-Prot
      Q3UKN7, Q80UB0
      Related
      ENSMUSP00000089157.6, ENSMUST00000091569.7
      Conserved Domains (2) summary
      smart00848
      Location:2987
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:114332
      Peptidase_C1; Papain family cysteine protease

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      60990426..61012230 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)