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    Wfdc21 WAP four-disulfide core domain 21 [ Mus musculus (house mouse) ]

    Gene ID: 66107, updated on 9-Dec-2024

    Summary

    Official Symbol
    Wfdc21provided by MGI
    Official Full Name
    WAP four-disulfide core domain 21provided by MGI
    Primary source
    MGI:MGI:1913357
    See related
    Ensembl:ENSMUSG00000051748 AllianceGenome:MGI:1913357
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Wdnm1-like; 1100001G20Rik
    Summary
    Enables enzyme activator activity. Acts upstream of or within response to lipopolysaccharide; response to tumor necrosis factor; and white fat cell differentiation. Located in extracellular space. Orthologous to human WFDC21P (WAP four-disulfide core domain 21, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in liver adult (RPKM 606.7), subcutaneous fat pad adult (RPKM 52.7) and 2 other tissues See more
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    Genomic context

    See Wfdc21 in Genome Data Viewer
    Location:
    11 C; 11 51.23 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (83637766..83643472)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (83746940..83752646)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 17 Neighboring gene WAP four-disulfide core domain 18 Neighboring gene STARR-positive B cell enhancer ABC_E3982 Neighboring gene STARR-positive B cell enhancer ABC_E9834 Neighboring gene HEAT repeat containing 6 Neighboring gene STARR-positive B cell enhancer ABC_E10701 Neighboring gene STARR-seq mESC enhancer starr_30205 Neighboring gene COMM domain containing 9 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183249.2NP_899072.1  protein Wfdc21 precursor

      See identical proteins and their annotated locations for NP_899072.1

      Status: VALIDATED

      Source sequence(s)
      AA254806, BY082582, BY094209
      Consensus CDS
      CCDS36258.1
      UniProtKB/Swiss-Prot
      Q8BTE6
      Related
      ENSMUSP00000064479.3, ENSMUST00000070832.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      83637766..83643472
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)