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    H2AC5P H2A clustered histone 5, pseudogene [ Homo sapiens (human) ]

    Gene ID: 10341, updated on 10-Dec-2024

    Summary

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    Official Symbol
    H2AC5Pprovided by HGNC
    Official Full Name
    H2A clustered histone 5, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:4728
    See related
    AllianceGenome:HGNC:4728
    Gene type
    pseudo
    RefSeq status
    INFERRED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    H2AFFP; pH2A/f; HIST1H2APS5
    Summary
    Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This histone pseudogene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Oct 2015]
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    Genomic context

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    See H2AC5P in Genome Data Viewer
    Location:
    6p22.2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (26043900..26044550)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (25912064..25912714)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (26044128..26044778)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:26033291-26033920 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24181 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24182 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24183 Neighboring gene H2A clustered histone 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24184 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24185 Neighboring gene H2B clustered histone 3 Neighboring gene H3 clustered histone 3 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:26053365-26053538 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:26053937-26054558 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:26055179-26055800 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24186 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24187 Neighboring gene H1.2 linker histone, cluster member

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Association of a human H1 histone gene with an H2A pseudogene and genes encoding H2B.1 and H3.1 histones. Kardalinou E, et al. J Cell Biochem, 1993 Aug. PMID 8227173

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • H2A histone family, member F, pseudogene
    • histone 1, H2a, pseudogene 5
    • histone cluster 1 H2A pseudogene 5
    • histone cluster 1, H2a, pseudogene 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029344.1 

      Range
      101..751
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      26043900..26044550
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      25912064..25912714
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_001227.1: Suppressed sequence

      Description
      NG_001227.1: This RefSeq was permanently suppressed because this gene is now included in the large histone family cluster on chromosome 6.
    Nucleotide Protein
    Heading Accession and Version

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