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    LINC02878 long intergenic non-protein coding RNA 2878 [ Homo sapiens (human) ]

    Gene ID: 286076, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC02878provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 2878provided by HGNC
    Primary source
    HGNC:HGNC:54524
    See related
    AllianceGenome:HGNC:54524
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BREA2
    Expression
    Broad expression in testis (RPKM 1.8), spleen (RPKM 0.8) and 18 other tissues See more
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    Genomic context

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    See LINC02878 in Genome Data Viewer
    Location:
    8q24.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (143697115..143698413)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (144853520..144854818)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (144779285..144780583)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375799 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:144751216-144751716 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:144751717-144752217 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:144764224-144764449 Neighboring gene zinc finger protein 707 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:144781964-144782464 Neighboring gene uncharacterized LOC101928160 Neighboring gene coiled-coil domain containing 166 Neighboring gene mitogen-activated protein kinase 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. lncRNA BREA2 promotes metastasis by disrupting the WWP2-mediated ubiquitination of Notch1. Zhang Z, et al. Proc Natl Acad Sci U S A, 2023 Feb 21. PMID 36795754, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. lncRNA BREA2 promotes metastasis by disrupting the WWP2-mediated ubiquitination of Notch1.
      Title: lncRNA BREA2 promotes metastasis by disrupting the WWP2-mediated ubiquitination of Notch1.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Other Names

    • breast cancer estrogen-induced apoptosis 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_015445.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AY940073

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      143697115..143698413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NT_187571.1 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      174162..175460
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      144853520..144854818
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001024610.1: Suppressed sequence

      Description
      NM_001024610.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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