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    LIPE-AS1 LIPE antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 100996307, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LIPE-AS1provided by HGNC
    Official Full Name
    LIPE antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:48589
    See related
    Ensembl:ENSG00000213904 AllianceGenome:HGNC:48589
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in fat (RPKM 4.9), testis (RPKM 3.5) and 23 other tissues See more
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    Genomic context

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    See LIPE-AS1 in Genome Data Viewer
    Location:
    19q13.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (42397148..42652355)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (45216534..45471772)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (42901300..43156507)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene multiple EGF like domains 8 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:42866515-42867014 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:42873179-42874132 Neighboring gene microRNA 8077 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10712 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10713 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14715 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:42901001-42901684 Neighboring gene uncharacterized LOC101930071 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:42901685-42902368 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10714 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:42910752-42911558 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14717 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14718 Neighboring gene cornifelin Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10715 Neighboring gene lipase E, hormone sensitive type Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10716 Neighboring gene C-X-C motif chemokine ligand 17 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:42969789-42970289 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr19:42975464-42976444 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr19:42977425-42978405 Neighboring gene MPRA-validated peak3491 silencer Neighboring gene RNA, U4 small nuclear 60, pseudogene Neighboring gene AN1-type zinc finger protein 5-like Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14720 Neighboring gene uncharacterized LOC105372407 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14721 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:43032933-43033795 Neighboring gene CEA cell adhesion molecule 1 Neighboring gene MPRA-validated peak3492 silencer Neighboring gene MPRA-validated peak3493 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:43064131-43064631 Neighboring gene CEA cell adhesion molecule pseudogene 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:43100409-43100909 Neighboring gene CEA cell adhesion molecule 8 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr19:43132188-43133387 Neighboring gene CEA cell adhesion molecule pseudogene 1 Neighboring gene CEA cell adhesion molecule pseudogene 5 Neighboring gene ribosomal protein S10 pseudogene 28

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Follicular fluid-derived exosomal LncRNA LIPE-AS1 modulates steroid metabolism and survival of granulosa cells leading to oocyte maturation arrest in polycystic ovary syndrome. Yu L, et al. J Assist Reprod Genet, 2024 May. PMID 38656738,
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Follicular fluid-derived exosomal LncRNA LIPE-AS1 modulates steroid metabolism and survival of granulosa cells leading to oocyte maturation arrest in polycystic ovary syndrome.
      Title: Follicular fluid-derived exosomal LncRNA LIPE-AS1 modulates steroid metabolism and survival of granulosa cells leading to oocyte maturation arrest in polycystic ovary syndrome.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Other Names

    • CTB-50E14.6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_073179.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC011497, AK096849, BM974950
      Related
      ENST00000594688.1

    2. NR_073180.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains two alternate exons, compared to variant 1.
      Source sequence(s)
      AK096849, AK311181, BM974950, DW455857
      Related
      ENST00000594624.8

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      42397148..42652355
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      45216534..45471772
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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