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    Ggnbp2 gametogenetin binding protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 217039, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ggnbp2provided by MGI
    Official Full Name
    gametogenetin binding protein 2provided by MGI
    Primary source
    MGI:MGI:2387356
    See related
    Ensembl:ENSMUSG00000020530 AllianceGenome:MGI:2387356
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DIF-3; Zfp403; D330017P12Rik
    Summary
    Acts upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of cell population proliferation; and negative regulation of protein phosphorylation. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; retina; and spleen. Orthologous to human GGNBP2 (gametogenetin binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 45.3), liver E14 (RPKM 28.4) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ggnbp2 in Genome Data Viewer
    Location:
    11 C; 11 51.34 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (84723187..84761668, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (84832361..84870837, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930502E09 gene Neighboring gene dehydrogenase/reductase 11 Neighboring gene STARR-positive B cell enhancer ABC_E3986 Neighboring gene STARR-seq mESC enhancer starr_30226 Neighboring gene STARR-seq mESC enhancer starr_30227 Neighboring gene STARR-positive B cell enhancer ABC_E7033 Neighboring gene gametogenetin binding protein 2, opposite strand Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class W Neighboring gene myosin XIX Neighboring gene zinc finger, HIT type 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    gametogenetin-binding protein 2
    Names
    dioxin inducible factor 3
    gametogenin binding protein 2
    zinc finger protein 403

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364111.1NP_001351040.1  gametogenetin-binding protein 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL596083, AL645623
      UniProtKB/TrEMBL
      H7BX83
    2. NM_001364112.1NP_001351041.1  gametogenetin-binding protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL596083, AL645623
      Consensus CDS
      CCDS88211.1
      UniProtKB/TrEMBL
      H7BX83
      Related
      ENSMUSP00000018547.3, ENSMUST00000018547.9
    3. NM_001364114.1NP_001351043.1  gametogenetin-binding protein 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL596083, AL645623
      Consensus CDS
      CCDS88210.1
      UniProtKB/Swiss-Prot
      A4QPD5, B7ZP33, Q5SV75, Q5SV76, Q5SV77, Q5SV78, Q6GVH6, Q6P9J4, Q920N4
      UniProtKB/TrEMBL
      H7BX83
      Related
      ENSMUSP00000130013.2, ENSMUST00000168434.8
    4. NM_001364115.1NP_001351044.1  gametogenetin-binding protein 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL596083, AL645623
      Consensus CDS
      CCDS88210.1
      UniProtKB/Swiss-Prot
      A4QPD5, B7ZP33, Q5SV75, Q5SV76, Q5SV77, Q5SV78, Q6GVH6, Q6P9J4, Q920N4
      UniProtKB/TrEMBL
      H7BX83
      Related
      ENSMUSP00000098252.4, ENSMUST00000100686.10
    5. NM_153144.3NP_694784.2  gametogenetin-binding protein 2 isoform 3

      See identical proteins and their annotated locations for NP_694784.2

      Status: VALIDATED

      Source sequence(s)
      AB064543, AL645623, AY633741, BE982217
      Consensus CDS
      CCDS36262.1
      UniProtKB/TrEMBL
      H7BX83
      Related
      ENSMUSP00000127584.2, ENSMUST00000172405.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      84723187..84761668 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245848.2XP_030101708.1  gametogenetin-binding protein 2 isoform X3

      UniProtKB/TrEMBL
      H7BX83
    2. XM_017314473.3XP_017169962.1  gametogenetin-binding protein 2 isoform X7

      UniProtKB/TrEMBL
      H7BX83
      Related
      ENSMUSP00000103716.3, ENSMUST00000108081.9
    3. XM_030245849.1XP_030101709.1  gametogenetin-binding protein 2 isoform X6

      UniProtKB/TrEMBL
      H7BX83
    4. XM_030245854.1XP_030101714.1  gametogenetin-binding protein 2 isoform X8

      UniProtKB/Swiss-Prot
      A4QPD5, B7ZP33, Q5SV75, Q5SV76, Q5SV77, Q5SV78, Q6GVH6, Q6P9J4, Q920N4
      UniProtKB/TrEMBL
      H7BX83
      Related
      ENSMUSP00000117482.3, ENSMUST00000154915.9
    5. XM_030245853.1XP_030101713.1  gametogenetin-binding protein 2 isoform X7

      UniProtKB/TrEMBL
      H7BX83
    6. XM_030245850.2XP_030101710.1  gametogenetin-binding protein 2 isoform X7

      UniProtKB/TrEMBL
      H7BX83
    7. XM_036156586.1XP_036012479.1  gametogenetin-binding protein 2 isoform X6

      UniProtKB/TrEMBL
      H7BX83
    8. XM_030245851.2XP_030101711.1  gametogenetin-binding protein 2 isoform X8

      UniProtKB/Swiss-Prot
      A4QPD5, B7ZP33, Q5SV75, Q5SV76, Q5SV77, Q5SV78, Q6GVH6, Q6P9J4, Q920N4
      UniProtKB/TrEMBL
      H7BX83
    9. XM_036156585.1XP_036012478.1  gametogenetin-binding protein 2 isoform X3

      UniProtKB/TrEMBL
      H7BX83
    10. XM_030245847.2XP_030101707.1  gametogenetin-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      H7BX83
    11. XM_030245846.2XP_030101706.1  gametogenetin-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      H7BX83
    12. XM_017314471.3XP_017169960.1  gametogenetin-binding protein 2 isoform X4

      UniProtKB/TrEMBL
      H7BX83
    13. XM_017314472.2XP_017169961.1  gametogenetin-binding protein 2 isoform X5

      UniProtKB/TrEMBL
      H7BX83