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    Zfp13 zinc finger protein 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287095, updated on 27-Nov-2024

    Summary

    Official Symbol
    Zfp13provided by RGD
    Official Full Name
    zinc finger protein 13provided by RGD
    Primary source
    RGD:1304577
    See related
    EnsemblRapid:ENSRNOG00000003455 AllianceGenome:RGD:1304577
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of hydrogen peroxide biosynthetic process; and positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrion and nucleus. Orthologous to human ZNF205 (zinc finger protein 205). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 30.8), Heart (RPKM 15.8) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Zfp13 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (13119707..13128284, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (12615455..12623615, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (12908643..12916784, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 213 Neighboring gene uncharacterized LOC120095040 Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene zinc finger and SCAN domain containing 10 Neighboring gene matrix metallopeptidase 25 Neighboring gene uncharacterized LOC102557038

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395554.1NP_001382483.1  zinc finger protein 205

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6GKB8
      Related
      ENSRNOP00000093521.2, ENSRNOT00000096198.2
      Conserved Domains (3) summary
      smart00349
      Location:114165
      KRAB; krueppel associated box
      COG5048
      Location:352512
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:406426
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      13119707..13128284 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268543.1XP_063124613.1  zinc finger protein 205 isoform X4

      UniProtKB/TrEMBL
      D3ZT76
    2. XM_063268540.1XP_063124610.1  zinc finger protein 205 isoform X2

      UniProtKB/TrEMBL
      A0A8I6GKB8
    3. XM_063268539.1XP_063124609.1  zinc finger protein 205 isoform X1

    4. XM_063268541.1XP_063124611.1  zinc finger protein 205 isoform X3

    5. XM_063268538.1XP_063124608.1  zinc finger protein 205 isoform X1

    6. XM_063268542.1XP_063124612.1  zinc finger protein 205 isoform X4

      UniProtKB/TrEMBL
      D3ZT76
      Related
      ENSRNOP00000004589.5, ENSRNOT00000004589.6
    7. XM_063268544.1XP_063124614.1  zinc finger protein 205 isoform X5

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001105765.1: Suppressed sequence

      Description
      NM_001105765.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.