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    Apobec4 apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498251, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Apobec4provided by RGD
    Official Full Name
    apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4provided by RGD
    Primary source
    RGD:1560256
    See related
    EnsemblRapid:ENSRNOG00000028089 AllianceGenome:RGD:1560256
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable hydrolase activity and metal ion binding activity. Predicted to be involved in mRNA processing. Orthologous to human APOBEC4 (apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 34.9), Brain (RPKM 16.0) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Apobec4 in Genome Data Viewer
    Location:
    13q21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (67436883..67444928)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (64887019..64895053)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (70157098..70165686)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene collagen beta(1-O)galactosyltransferase 2 Neighboring gene ral guanine nucleotide dissociation stimulator like 1 Neighboring gene uncharacterized LOC102551528 Neighboring gene uncharacterized LOC134481515 Neighboring gene actin related protein 2/3 complex, subunit 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative C->U-editing enzyme APOBEC-4
    Names
    apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
    NP_001017492.1
    XP_038946893.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017492.2 → NP_001017492.1  putative C->U-editing enzyme APOBEC-4

      See identical proteins and their annotated locations for NP_001017492.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/Swiss-Prot
      Q6AXX9
      UniProtKB/TrEMBL
      A6ICT9
      Conserved Domains (1) summary
      pfam18778
      Location:42 → 229
      NAD1; Novel AID APOBEC clade 1

    2. NM_001429855.1 → NP_001416784.1  putative C->U-editing enzyme APOBEC-4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/Swiss-Prot
      Q6AXX9
      UniProtKB/TrEMBL
      A6ICT9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      67436883..67444928
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039090965.2 → XP_038946893.1  putative C->U-editing enzyme APOBEC-4 isoform X1

      Related
      ENSRNOP00000034180.3, ENSRNOT00000036906.6
      Conserved Domains (1) summary
      pfam18778
      Location:42 → 229
      NAD1; Novel AID APOBEC clade 1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AXX9.1 GenPept UniProtKB/Swiss-Prot:Q6AXX9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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