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    Zfp184 zinc finger protein 184 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306966, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp184provided by RGD
    Official Full Name
    zinc finger protein 184provided by RGD
    Primary source
    RGD:1304798
    See related
    EnsemblRapid:ENSRNOG00000061612 AllianceGenome:RGD:1304798
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf184
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF184 (zinc finger protein 184). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 35.3), Thymus (RPKM 33.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp184 in Genome Data Viewer
    Location:
    17p11
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (47262566..47299675, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (42588140..42603905, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (44625795..44645549, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene POM121 transmembrane nucleoporin-like 2 Neighboring gene transfer RNA methionine (anticodon CAU) 7 Neighboring gene Tu translation elongation factor, mitochondrial, pseudogene 3 Neighboring gene transfer RNA serine (anticodon AGA) 7 Neighboring gene uncharacterized LOC102555506 Neighboring gene transfer RNA serine (anticodon AGA) 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 184
    Names
    zinc finger protein 184 (Kruppel-like)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427199.1 → NP_001414128.1  zinc finger protein 184

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A8I6AS09, A6KNA5
      Related
      ENSRNOP00000069240.3, ENSRNOT00000077628.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      47262566..47299675 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276446.1 → XP_063132516.1  zinc finger protein 184 isoform X5

      UniProtKB/TrEMBL
      A0A0G2K6X3, F1M7P0

    2. XM_039096163.2 → XP_038952091.1  zinc finger protein 184 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AS09, A6KNA5
      Conserved Domains (3) summary
      smart00349
      Location:28 → 88
      KRAB; krueppel associated box
      COG5048
      Location:203 → 635
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:288 → 308
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_063276444.1 → XP_063132514.1  zinc finger protein 184 isoform X3

      UniProtKB/TrEMBL
      A0A0G2JUV0
      Related
      ENSRNOP00000097886.2, ENSRNOT00000099295.2

    4. XM_063276443.1 → XP_063132513.1  zinc finger protein 184 isoform X2

    5. XM_063276445.1 → XP_063132515.1  zinc finger protein 184 isoform X3

      UniProtKB/TrEMBL
      A0A0G2JUV0

    6. XM_003751710.6 → XP_003751758.1  zinc finger protein 184 isoform X1

      See identical proteins and their annotated locations for XP_003751758.1

      UniProtKB/TrEMBL
      A0A8I6AS09, A6KNA5
      Conserved Domains (3) summary
      smart00349
      Location:28 → 88
      KRAB; krueppel associated box
      COG5048
      Location:203 → 635
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:288 → 308
      ZF_C2H2; C2H2 Zn finger [structural motif]

    7. XM_039096165.2 → XP_038952093.1  zinc finger protein 184 isoform X3

      UniProtKB/TrEMBL
      A0A0G2JUV0
      Conserved Domains (4) summary
      COG5048
      Location:252 → 660
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:122 → 272
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:256 → 276
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:27 → 68
      KRAB; KRAB box

    8. XM_039096164.2 → XP_038952092.1  zinc finger protein 184 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:28 → 75
      KRAB; krueppel associated box
      COG5048
      Location:190 → 622
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:275 → 295
      ZF_C2H2; C2H2 Zn finger [structural motif]

    9. XM_006254113.5 → XP_006254175.1  zinc finger protein 184 isoform X1

      See identical proteins and their annotated locations for XP_006254175.1

      UniProtKB/TrEMBL
      A0A8I6AS09, A6KNA5
      Conserved Domains (3) summary
      smart00349
      Location:28 → 88
      KRAB; krueppel associated box
      COG5048
      Location:203 → 635
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:288 → 308
      ZF_C2H2; C2H2 Zn finger [structural motif]

    10. XM_006254118.5 → XP_006254180.1  zinc finger protein 184 isoform X4

      See identical proteins and their annotated locations for XP_006254180.1

      UniProtKB/TrEMBL
      A0A0G2JUV0
      Conserved Domains (3) summary
      COG5048
      Location:209 → 617
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:79 → 229
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:213 → 233
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001100573.1: Suppressed sequence

      Description
      NM_001100573.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from cow: ZNF184 (GeneID:515674).
    Nucleotide Protein Strain
    Heading Accession and Version

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