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    CG31683 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 261623, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31683provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051683
    Locus tag
    Dmel_CG31683
    See related
    AllianceGenome:FB:FBgn0051683
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH02384; Dmel\CG31683
    Summary
    Enables serine hydrolase activity. Predicted to be involved in lipid metabolic process. Is expressed in adult fat body. Human ortholog(s) of this gene implicated in Norum disease and arteriosclerosis. Orthologous to several human genes including PLA2G15 (phospholipase A2 group XV). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31683 in Genome Data Viewer
    Location:
    38C7-38C7; 2-54 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20447734..20449964, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20447734..20449964, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43607 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cell division cycle 23 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A field-based quantitative analysis of sublethal effects of air pollution on pollinators. Thimmegowda GG, et al. Proc Natl Acad Sci U S A, 2020 Aug 25. PMID 32778582, Free PMC Article
    2. RNAi screening of Drosophila (Sophophora) melanogaster S2 cells for ricin sensitivity and resistance. Pawar V, et al. J Biomol Screen, 2011 Apr. PMID 21364088, Free PMC Article
    3. Exploring the correlation between deltamethrin stress and Keap1-Nrf2-ARE pathway from Drosophila melanogaster RNASeq data. Liu Y, et al. Genomics, 2020 Mar. PMID 31376529
    4. Fat body-specific reduction of CTPS alleviates HFD-induced obesity. Liu J, et al. Elife, 2023 Sep 11. PMID 37695169, Free PMC Article
    5. Novel regulators of planar cell polarity: a genetic analysis in Drosophila. Weber U, et al. Genetics, 2012 May. PMID 22391484, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine hydrolase activity HDA PubMed 
    Process Evidence Code Pubs
    involved_in lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31683-PA
    CG31683-PB
    sterol o-acyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20447734..20449964 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165330.3 → NP_724265.2  uncharacterized protein Dmel_CG31683, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724265.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      C3KGK6, Q8INV2, Q9Y168
      Related
      FBpp0080897
      Conserved Domains (1) summary
      cl21494
      Location:81 → 405
      Abhydrolase; alpha/beta hydrolases

    2. NM_001273697.1 → NP_001260626.1  uncharacterized protein Dmel_CG31683, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260626.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C3KGK6, Q8INV2, Q9Y168
      Conserved Domains (1) summary
      cl21494
      Location:81 → 405
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Y168 Q9Y168

    Gene LinkOut

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