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    Tim10 Translocase of inner membrane 10 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37478, updated on 4-Jan-2025

    Summary

    Official Symbol
    Tim10provided by FlyBase
    Official Full Name
    Translocase of inner membrane 10provided by FlyBase
    Primary source
    FLYBASE:FBgn0027360
    Locus tag
    Dmel_CG9878
    See related
    AllianceGenome:FB:FBgn0027360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    bs31d12.y1; CG9878; Dmel\CG9878; Dromel_CG9878_FBtr0071676_tim10_mORF; tim10
    Summary
    Involved in defense response to Gram-negative bacterium and negative regulation of innate immune response. Predicted to be part of TIM22 mitochondrial import inner membrane insertion complex and mitochondrial intermembrane space protein transporter complex. Predicted to be active in mitochondrial inner membrane. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; and gut section. Orthologous to human TIMM10 (translocase of inner mitochondrial membrane 10). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See Tim10 in Genome Data Viewer
    Location:
    57F8-57F8; 2-96 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21690215..21691139, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17577720..17578644, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit k Neighboring gene TATA binding protein Neighboring gene Baramicin C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Phosphopantothenoylcysteine decarboxylase Neighboring gene Cyclic nucleotide-gated ion channel subunit B Neighboring gene HMG protein Z Neighboring gene High mobility group protein D

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    translocase of inner membrane 10
    Names
    CG9878-PA
    CG9878-PB
    Tim10-PA
    Tim10-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21690215..21691139 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137762.4NP_611606.1  translocase of inner membrane 10, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611606.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B7YZS2, Q0E8Z5, Q9W2D6, Q9Y0V7
      UniProtKB/TrEMBL
      A0A1B2AKF1
      Related
      FBpp0071593
      Conserved Domains (1) summary
      pfam02953
      Location:1576
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    2. NM_166474.3NP_726104.1  translocase of inner membrane 10, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726104.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B7YZS2, Q0E8Z5, Q9W2D6, Q9Y0V7
      UniProtKB/TrEMBL
      A0A1B2AKF1
      Related
      FBpp0071594
      Conserved Domains (1) summary
      pfam02953
      Location:1576
      zf-Tim10_DDP; Tim10/DDP family zinc finger