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    CG10286 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40786, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10286provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037439
    Locus tag
    Dmel_CG10286
    See related
    AllianceGenome:FB:FBgn0037439
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10286
    Summary
    Predicted to enable unfolded protein binding activity. Predicted to be involved in protein import into nucleus and ribosomal large subunit biogenesis. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut primordium; gland; larval muscle cell; and nephrocyte. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia. Orthologous to human HEATR3 (HEAT repeat containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10286 in Genome Data Viewer
    Location:
    83E4-83E4; 3-47.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6368965..6371115)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2194687..2196837)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene p21-activated kinase Neighboring gene uncharacterized protein Neighboring gene Carnitine O-Acetyl-Transferase Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Circulating glucose levels inversely correlate with Drosophila larval feeding through insulin signaling and SLC5A11. Ugrankar R, et al. Commun Biol, 2018. PMID 30271990, Free PMC Article
    2. A Drosophila LexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research. Kockel L, et al. G3 (Bethesda), 2016 Oct 13. PMID 27527793, Free PMC Article
    3. Systems genetics of complex traits in Drosophila melanogaster. Ayroles JF, et al. Nat Genet, 2009 Mar. PMID 19234471, Free PMC Article
    4. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    5. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10286-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6368965..6371115
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141392.3 → NP_649649.1  uncharacterized protein Dmel_CG10286 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649649.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI15
      Related
      FBpp0081214
      Conserved Domains (1) summary
      cd13394
      Location:41 → 621
      Syo1_like; Fungal symportin 1 (syo1) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VI15 Q9VI15

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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