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    Atpalpha sodium/potassium-transporting ATPase subunit alpha [ Anopheles gambiae (African malaria mosquito) ]

    Gene ID: 1273109, updated on 3-Dec-2024

    Summary

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    Gene symbol
    Atpalpha
    Gene description
    sodium/potassium-transporting ATPase subunit alpha
    See related
    VectorBase:AGAMI1_014754
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles gambiae
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Also known as
    AGAP002858
    Orthologs
    fruit fly all
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    Genomic context

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    See Atpalpha in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 2 NC_064601.1 (28168430..28233706)

    Chromosome 2 - NC_064601.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC11176035 Neighboring gene uncharacterized LOC133391432 Neighboring gene Niemann-Pick type C-2b Neighboring gene sodium/calcium exchanger 3 Neighboring gene probable cytochrome P450 6a14 Neighboring gene cytochrome P450 6a22 Neighboring gene neuroligin-4, X-linked

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064601.1 Chromosome 2 Reference idAnoGambNW_F1_1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pilot Anopheles gambiae full-length cDNA study: sequencing and initial characterization of 35,575 clones. Gomez SM, et al. Genome Biol, 2005. PMID 15833126, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables P-type sodium:potassium-exchanging transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular potassium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular sodium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion export across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium/potassium-transporting ATPase subunit alpha
    Names
    AGAP002858-PA
    AGAP002858-PB
    AGAP002858-PC
    AGAP002858-PD
    AGAP002858-PE

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference idAnoGambNW_F1_1 Primary Assembly

    Genomic

    1. NC_064601.1 Reference idAnoGambNW_F1_1 Primary Assembly

      Range
      28168430..28233706
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_061645845.1 → XP_061501829.1  sodium/potassium-transporting ATPase subunit alpha isoform X4

      UniProtKB/TrEMBL
      F5HKJ1

    2. XM_061645842.1 → XP_061501826.1  sodium/potassium-transporting ATPase subunit alpha isoform X1

      UniProtKB/TrEMBL
      F5HKJ1

    3. XM_061645844.1 → XP_061501828.1  sodium/potassium-transporting ATPase subunit alpha isoform X3

      UniProtKB/TrEMBL
      F5HKJ1

    4. XM_061645843.1 → XP_061501827.1  sodium/potassium-transporting ATPase subunit alpha isoform X2

      UniProtKB/TrEMBL
      F5HKJ1

    5. XM_061645848.1 → XP_061501832.1  sodium/potassium-transporting ATPase subunit alpha isoform X6

      UniProtKB/TrEMBL
      F5HKJ2

    6. XM_061645850.1 → XP_061501834.1  sodium/potassium-transporting ATPase subunit alpha isoform X8

      UniProtKB/TrEMBL
      F5HKJ2

    7. XM_061645849.1 → XP_061501833.1  sodium/potassium-transporting ATPase subunit alpha isoform X7

      UniProtKB/TrEMBL
      F5HKJ2

    8. XM_003436220.2 → XP_003436268.1  sodium/potassium-transporting ATPase subunit alpha isoform X10

      See identical proteins and their annotated locations for XP_003436268.1

      UniProtKB/TrEMBL
      F5HKJ2, F5HKJ4
      Conserved Domains (1) summary
      TIGR01106
      Location:4 → 1000
      ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit

    9. XM_061645846.1 → XP_061501830.1  sodium/potassium-transporting ATPase subunit alpha isoform X5

      UniProtKB/TrEMBL
      F5HKJ1

    10. XM_061645847.1 → XP_061501831.1  sodium/potassium-transporting ATPase subunit alpha isoform X5

      UniProtKB/TrEMBL
      F5HKJ1

    11. XM_003436221.2 → XP_003436269.1  sodium/potassium-transporting ATPase subunit alpha isoform X10

      See identical proteins and their annotated locations for XP_003436269.1

      UniProtKB/TrEMBL
      F5HKJ2, F5HKJ4
      Conserved Domains (1) summary
      TIGR01106
      Location:4 → 1000
      ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit

    12. XM_061645855.1 → XP_061501839.1  sodium/potassium-transporting ATPase subunit alpha isoform X10

      UniProtKB/TrEMBL
      F5HKJ2, F5HKJ4

    13. XM_061645853.1 → XP_061501837.1  sodium/potassium-transporting ATPase subunit alpha isoform X10

      UniProtKB/TrEMBL
      F5HKJ2, F5HKJ4

    14. XM_061645852.1 → XP_061501836.1  sodium/potassium-transporting ATPase subunit alpha isoform X9

      UniProtKB/TrEMBL
      F5HKJ2, Q7PGN1

    15. XM_061645854.1 → XP_061501838.1  sodium/potassium-transporting ATPase subunit alpha isoform X10

      UniProtKB/TrEMBL
      F5HKJ2, F5HKJ4
    Nucleotide Protein Strain
    Heading Accession and Version

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