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    ste14 isoprenylcysteine carboxylmethyltransferase ste14 [ Anopheles gambiae (African malaria mosquito) ]

    Gene ID: 1281867, updated on 22-Jun-2024

    Summary

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    Gene symbol
    ste14
    Gene description
    isoprenylcysteine carboxylmethyltransferase ste14
    See related
    VectorBase:AGAMI1_014497
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles gambiae
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Also known as
    AGAP001310
    Orthologs
    fruit fly all
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    Genomic context

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    See ste14 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 2 NC_064601.1 (2838871..2841152, complement)

    Chromosome 2 - NC_064601.1Genomic Context describing neighboring genes Neighboring gene ubiquitin fusion-degradation 1-like Neighboring gene Actin-related protein 2/3 complex, subunit 4 Neighboring gene bicaudal D-related protein homolog Neighboring gene Coiled-coil domain containing protein 114 Neighboring gene succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial Neighboring gene mitochondrial ribosomal protein L20

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064601.1 Chromosome 2 Reference idAnoGambNW_F1_1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutational analysis of the integral membrane methyltransferase isoprenylcysteine carboxyl methyltransferase (ICMT) reveals potential substrate binding sites. Diver MM, et al. J Biol Chem, 2014 Sep 19. PMID 25059662, Free PMC Article
    2. Pilot Anopheles gambiae full-length cDNA study: sequencing and initial characterization of 35,575 clones. Gomez SM, et al. Genome Biol, 2005. PMID 15833126, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The active site of ICMT spans both cytosolic and membrane-embedded regions of the protein.
      Title: Mutational analysis of the integral membrane methyltransferase isoprenylcysteine carboxyl methyltransferase (ICMT) reveals potential substrate binding sites.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in C-terminal protein methylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein-S-isoprenylcysteine O-methyltransferase
    Names
    AGAP001310-PA
    Protein-S-isoprenylcysteine O-methyltransferase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference idAnoGambNW_F1_1 Primary Assembly

    Genomic

    1. NC_064601.1 Reference idAnoGambNW_F1_1 Primary Assembly

      Range
      2838871..2841152 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_321837.4 → XP_321837.4  protein-S-isoprenylcysteine O-methyltransferase

    Nucleotide Protein Strain
    Heading Accession and Version

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