U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PF3D7_1118600 histone acetyltransferase MYST [ Plasmodium falciparum 3D7 ]

    Gene ID: 810739, updated on 12-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PF3D7_1118600
    Gene description
    histone acetyltransferase MYST
    Locus tag
    PF3D7_1118600
    See related
    PlasmoDB:PF3D7_1118600; VEuPathDB:PF3D7_1118600
    Gene type
    protein coding
    RNA name
    histone acetyltransferase MYST
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PF3D7_1118600 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    1
    Sequence:
    Chromosome: 11; NC_037282.1 (705556..707382, complement)

    Chromosome 11 - NC_037282.1Genomic Context describing neighboring genes Neighboring gene haloacid dehalogenase-like hydrolase, putative Neighboring gene Nop56/Sik1-like protein, putative Neighboring gene myosin light chain B Neighboring gene actin-related protein 2/3 complex subunit 1, putative

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037282.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Inhibition of PfMYST Histone Acetyltransferase Activity Blocks Plasmodium falciparum Growth and Survival. Sen U, et al. Antimicrob Agents Chemother, 2020 Dec 16. PMID 33046499, Free PMC Article
    2. The MYST family histone acetyltransferase regulates gene expression and cell cycle in malaria parasite Plasmodium falciparum. Miao J, et al. Mol Microbiol, 2010 Nov. PMID 20807207, Free PMC Article
    3. Plasmodium falciparum RUVBL3 protein: a novel DNA modifying enzyme and an interacting partner of essential HAT protein MYST. Sen U, et al. Sci Rep, 2018 Jul 19. PMID 30026605, Free PMC Article
    4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Collectively, this study showed that PfMYST plays important roles in cellular processes such as gene activation, cell cycle control and DNA repair.
      Title: The MYST family histone acetyltransferase regulates gene expression and cell cycle in malaria parasite Plasmodium falciparum.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables histone acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to xenobiotic stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in host cell periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in symbiont-containing vacuole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    histone acetyltransferase MYST
    XP_001347863.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037282.1 Reference assembly

      Range
      705556..707382 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001347827.1 → XP_001347863.1  histone acetyltransferase MYST [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001347863.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024X7F6, A0A0L7KAP8, A0A0L7LYJ6, Q8III2, W4IE39, W4ISR7, W7JTB1
      Conserved Domains (1) summary
      PLN00104
      Location:260 → 601
      PLN00104; MYST -like histone acetyltransferase; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous