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    PF3D7_1239600 hydroxyethylthiazole kinase [ Plasmodium falciparum 3D7 ]

    Gene ID: 811436, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1239600
    Gene description
    hydroxyethylthiazole kinase
    Locus tag
    PF3D7_1239600
    See related
    PlasmoDB:PF3D7_1239600; VEuPathDB:PF3D7_1239600
    Gene type
    protein coding
    RNA name
    hydroxyethylthiazole kinase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
    NEW
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    Genomic context

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    See PF3D7_1239600 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    1
    Sequence:
    Chromosome: 12; NC_037284.1 (1652936..1653844, complement)

    Chromosome 12 - NC_037284.1Genomic Context describing neighboring genes Neighboring gene conserved protein, unknown function Neighboring gene DNA gyrase subunit B Neighboring gene ATP-dependent zinc metalloprotease FTSH 1 Neighboring gene conserved Plasmodium protein, unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037284.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation, characterization, interaction of a thiazolekinase (Plasmodium falciparum) with silver nanoparticles. Yao J, et al. Int J Biol Macromol, 2015 Aug. PMID 26049116
    2. Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368868
    3. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Plasmodium falciparum thiazolekinase has been cloned and characterized.
      Title: Isolation, characterization, interaction of a thiazolekinase (Plasmodium falciparum) with silver nanoparticles.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables hydroxyethylthiazole kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within thiamine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydroxyethylthiazole kinase
    XP_001350790.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037284.1 Reference assembly

      Range
      1652936..1653844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001350754.1 → XP_001350790.1  hydroxyethylthiazole kinase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001350790.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V5A3, A0A024VMI8, A0A024W3X0, A0A024WM19, A0A024X3U0, A0A0L0CUZ8, A0A0L1I9T4, A0A0L7KH75, A0A0L7M6U3, Q8I527, W4ICZ8, W4J227, W7F943, W7G1G4, W7JJT2, W7JRC8
      Conserved Domains (1) summary
      cd01170
      Location:33 → 282
      THZ_kinase; 4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine ...
    Nucleotide Protein
    Heading Accession and Version

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