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    Xpd general transcription and DNA repair factor IIH helicase subunit XPD [ Anopheles gambiae (African malaria mosquito) ]

    Gene ID: 1272969, updated on 22-Jun-2024

    Summary

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    Gene symbol
    Xpd
    Gene description
    general transcription and DNA repair factor IIH helicase subunit XPD
    See related
    VectorBase:AGAMI1_004304
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles gambiae
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Also known as
    AGAP002988
    Orthologs
    fruit fly all
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    Genomic context

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    See Xpd in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 2 NC_064601.1 (30521557..30524415)

    Chromosome 2 - NC_064601.1Genomic Context describing neighboring genes Neighboring gene methionine sulfoxide reductase SelR Neighboring gene serine/threonine-protein kinase PAK 3-like protein Neighboring gene GILT-like protein 1 Neighboring gene Ras-related GTP binding A/B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064601.1 Chromosome 2 Reference idAnoGambNW_F1_1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pilot Anopheles gambiae full-length cDNA study: sequencing and initial characterization of 35,575 clones. Gomez SM, et al. Genome Biol, 2005. PMID 15833126, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nucleotide-excision repair, DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of mitotic recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    general transcription and DNA repair factor IIH helicase subunit XPD
    Names
    AGAP002988-PA
    DNA excision repair protein ERCC-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference idAnoGambNW_F1_1 Primary Assembly

    Genomic

    1. NC_064601.1 Reference idAnoGambNW_F1_1 Primary Assembly

      Range
      30521557..30524415
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_311900.6 → XP_311900.4  general transcription and DNA repair factor IIH helicase subunit XPD

      See identical proteins and their annotated locations for XP_311900.4

      UniProtKB/TrEMBL
      Q7QD77
      Conserved Domains (1) summary
      TIGR00604
      Location:7 → 708
      rad3; DNA repair helicase (rad3)
    Nucleotide Protein Strain
    Heading Accession and Version

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