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    PF3D7_1216600 cell traversal protein for ookinetes and sporozoites [ Plasmodium falciparum 3D7 ]

    Gene ID: 811213, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1216600
    Gene description
    cell traversal protein for ookinetes and sporozoites
    Locus tag
    PF3D7_1216600
    See related
    PlasmoDB:PF3D7_1216600; VEuPathDB:PF3D7_1216600
    Gene type
    protein coding
    RNA name
    cell traversal protein for ookinetes and sporozoites
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1216600 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    1
    Sequence:
    Chromosome: 12; NC_037284.1 (659738..660286, complement)

    Chromosome 12 - NC_037284.1Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium membrane protein, unknown function Neighboring gene male development gene 1 Neighboring gene perforin-like protein 2 Neighboring gene tRNA-Pro

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037284.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plasmodium yoelii S4/CelTOS is important for sporozoite gliding motility and cell traversal. Steel RWJ, et al. Cell Microbiol, 2018 Apr. PMID 29253313
    2. CelTOS, a novel malarial protein that mediates transmission to mosquito and vertebrate hosts. Kariu T, et al. Mol Microbiol, 2006 Mar. PMID 16468982
    3. Systematic Identification of Plasmodium Falciparum Sporozoite Membrane Protein Interactions Reveals an Essential Role for the p24 Complex in Host Infection. Knöckel J, et al. Mol Cell Proteomics, 2021. PMID 33515807, Free PMC Article
    4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell gliding ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in microneme ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cell traversal protein for ookinetes and sporozoites

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037284.1 Reference assembly

      Range
      659738..660286 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001350533.1 → XP_001350569.1  cell traversal protein for ookinetes and sporozoites [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001350569.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024VMX1, Q53UB8, Q8I5P1, W7JS91, W7JVD3
      Conserved Domains (1) summary
      pfam18659
      Location:39 → 154
      CelTOS; Cell-traversal protein for ookinetes and sporozoites
    Nucleotide Protein
    Heading Accession and Version

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