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    Smox spermine oxidase [ Mus musculus (house mouse) ]

    Gene ID: 228608, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Smoxprovided by MGI
    Official Full Name
    spermine oxidaseprovided by MGI
    Primary source
    MGI:MGI:2445356
    See related
    Ensembl:ENSMUSG00000027333 AllianceGenome:MGI:2445356
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PAO; SMO; PAOh1; B130066H01Rik
    Summary
    Enables polyamine oxidase activity. Acts upstream of or within spermine catabolic process. Predicted to be located in cytosol; nuclear membrane; and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including cerebral cortex; extraembryonic component; and placenta. Orthologous to human SMOX (spermine oxidase). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in liver E14.5 (RPKM 27.2), liver E14 (RPKM 26.0) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Smox in Genome Data Viewer
    Location:
    2 F1; 2 63.45 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (131333624..131367103)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (131491858..131525183)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10147 Neighboring gene aldo-keto reductase family 1 member A1-like Neighboring gene predicted gene 14304 Neighboring gene predicted gene, 30679 Neighboring gene STARR-seq mESC enhancer starr_05713 Neighboring gene predicted gene, 30732 Neighboring gene predicted gene, 39938 Neighboring gene adrenergic receptor, alpha 1d

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Spermine oxidase regulates liver inflammation and fibrosis through β-catenin pathway. Hu T, et al. Clin Res Hepatol Gastroenterol, 2024 Aug. PMID 39002816
    2. Emerging Role for Linear and Circular Spermine Oxidase RNAs in Skeletal Muscle Physiopathology. Reinoso-Sánchez JF, et al. Int J Mol Sci, 2020 Nov 3. PMID 33153123, Free PMC Article
    3. Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase mu isoform. Bianchi M, et al. FEBS J, 2005 Jun. PMID 15955064
    4. Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling. Sierra JC, et al. Oncogene, 2020 May. PMID 32350444, Free PMC Article
    5. Epileptic seizures and oxidative stress in a mouse model over-expressing spermine oxidase. Leonetti A, et al. Amino Acids, 2020 Feb. PMID 31197571

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Spermine oxidase regulates liver inflammation and fibrosis through beta-catenin pathway.
      Title: Spermine oxidase regulates liver inflammation and fibrosis through β-catenin pathway.
    2. Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
      Title: Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
    3. Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
      Title: Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
    4. Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia.
      Title: Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia.
    5. Emerging Role for Linear and Circular Spermine Oxidase RNAs in Skeletal Muscle Physiopathology.
      Title: Emerging Role for Linear and Circular Spermine Oxidase RNAs in Skeletal Muscle Physiopathology.
    6. Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
      Title: Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
    7. Epileptic seizures and oxidative stress in a mouse model over-expressing spermine oxidase.
      Title: Epileptic seizures and oxidative stress in a mouse model over-expressing spermine oxidase.
    8. High SMOX expression is associated with neuroblastoma.
      Title: Link between spermine oxidase and apoptosis antagonizing transcription factor: A new pathway in neuroblastoma.
    9. Our studies indicate that SMOX has immunomodulatory effects in experimental colitis via polyamine flux. Thus, SMOX contributes to the immunopathogenesis of C. rodentium infection, but is protective in DSS colitis, indicating the divergent effects of spermidine.
      Title: Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection.
    10. Dach-SMOX transgenic mouse can be considered as a suitable in vivo genetic model to study the involvement of spermine oxidase in excitotoxicity.
      Title: Glutamate Excitotoxicity Linked to Spermine Oxidase Overexpression.
    Submit: New GeneRIF Correction See all GeneRIFs (18)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2)  1 citation

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables polyamine oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polyamine oxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables polyamine oxidase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables spermine oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in polyamine catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in spermine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within spermine catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in spermine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermine catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    spermine oxidase
    Names
    PAO-1
    polyamine oxidase 1
    NP_001171304.1
    NP_001171305.1
    NP_001171306.1
    NP_001171307.1
    NP_001171308.1
    NP_001171309.1
    NP_001171310.1
    NP_001171311.1
    NP_663508.1
    XP_006499350.1
    XP_006499351.1
    XP_006499352.1
    XP_006499353.1
    XP_006499354.1
    XP_006499355.1
    XP_006499356.1
    XP_011237777.1
    XP_017173258.1
    XP_030106328.1
    XP_030106330.1
    XP_030106332.1
    XP_030106336.1
    XP_030106341.1
    XP_030106346.1
    XP_030106347.1
    XP_030106354.1
    XP_030106358.1
    XP_030106360.1
    XP_030106369.1
    XP_030106371.1
    XP_030106373.1
    XP_036017254.1
    XP_036017255.1
    XP_036017256.1
    XP_036017258.1
    XP_036017259.1
    XP_036017261.1
    XP_036017262.1
    XP_036017263.1
    XP_036017264.1
    XP_036017276.1
    XP_036017285.1
    XP_036017288.1
    XP_036017293.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177833.2 → NP_001171304.1  spermine oxidase isoform a

      See identical proteins and their annotated locations for NP_001171304.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longest transcript and it encodes the longest protein (isoform a). This variant has also been called 'splice variant mu'.
      Source sequence(s)
      AL831731, AL831781
      Consensus CDS
      CCDS50719.1
      UniProtKB/Swiss-Prot
      Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Related
      ENSMUSP00000105815.3, ENSMUST00000110186.9
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 578
      PLN02568; polyamine oxidase

    2. NM_001177834.2 → NP_001171305.1  spermine oxidase isoform c

      See identical proteins and their annotated locations for NP_001171305.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses a different splice site and lacks an alternate exon, which shifts the reading frame, compared to variant 1. The resulting protein (isoform c) is shorter and has a distinct C-terminus when it is compared to isoform a. This variant has also been called 'splice variant beta'.
      Source sequence(s)
      AL831731, AL831781
      Consensus CDS
      CCDS50720.1
      UniProtKB/Swiss-Prot
      Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Related
      ENSMUSP00000105817.2, ENSMUST00000110188.8
      Conserved Domains (2) summary
      PLN02568
      Location:50 → 457
      PLN02568; polyamine oxidase
      pfam13450
      Location:45 → 88
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    3. NM_001177835.2 → NP_001171306.1  spermine oxidase isoform d

      See identical proteins and their annotated locations for NP_001171306.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks two alternate exons which shifts the reading frame, compared to variant 1. The resulting protein (isoform d) is shorter and has a distinct C-terminus when it is compared to isoform a. This transcript has also been called 'splice variant gamma'.
      Source sequence(s)
      AL831731, AL831781
      Consensus CDS
      CCDS50721.1
      UniProtKB/Swiss-Prot
      Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Related
      ENSMUSP00000105818.3, ENSMUST00000110189.9
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 445
      PLN02568; polyamine oxidase

    4. NM_001177836.2 → NP_001171307.1  spermine oxidase isoform e

      See identical proteins and their annotated locations for NP_001171307.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) uses a different splice site and lacks an alternate, in-frame exon, compared to variant 1. The resulting protein (isoform e) is shorter when it is compared to isoform a. This transcript and protein have also been called 'polyamine oxidase-m'.
      Source sequence(s)
      AL831731, AL831781
      Consensus CDS
      CCDS50718.1
      UniProtKB/Swiss-Prot
      Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Related
      ENSMUSP00000105809.2, ENSMUST00000110180.2
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 412
      PLN02568; polyamine oxidase

    5. NM_001177837.2 → NP_001171308.1  spermine oxidase isoform f

      See identical proteins and their annotated locations for NP_001171308.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) uses a different splice site and lacks an alternate, in-frame exon, compared to variant 1. The resulting protein (isoform f) is shorter when it is compared to isoform a.
      Source sequence(s)
      AL831731, AL831781
      Consensus CDS
      CCDS50722.1
      UniProtKB/TrEMBL
      Q3TLR8
      Related
      ENSMUSP00000105810.2, ENSMUST00000110181.8
      Conserved Domains (2) summary
      pfam01593
      Location:45 → 374
      Amino_oxidase; Flavin containing amine oxidoreductase
      pfam13450
      Location:45 → 88
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    6. NM_001177838.2 → NP_001171309.1  spermine oxidase isoform g

      See identical proteins and their annotated locations for NP_001171309.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) lacks three alternate exons but maintains the reading frame, compared to variant 1. The resulting protein (isoform g) is shorter when it is compared to isoform a. This transcript has also been called 'splice variant phi'.
      Source sequence(s)
      AL831731, AL831781
      Consensus CDS
      CCDS50724.1
      UniProtKB/Swiss-Prot
      Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Related
      ENSMUSP00000105812.3, ENSMUST00000110183.9
      Conserved Domains (1) summary
      pfam13450
      Location:45 → 88
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    7. NM_001177839.2 → NP_001171310.1  spermine oxidase isoform h

      See identical proteins and their annotated locations for NP_001171310.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) lacks two alternate exons, which changes the reading frame and results in a premature stop codon, compared to variant 1. The resulting protein (isoform h) has a shorter and distinct C-terminus when it is compared to isoform a. This transcript has also been called 'splice variant epsilon' and 'polyamine oxidase-s'.
      Source sequence(s)
      AL831731, AL831781
      Consensus CDS
      CCDS50723.1
      UniProtKB/TrEMBL
      A2ANQ4
      Related
      ENSMUSP00000105808.3, ENSMUST00000110179.9
      Conserved Domains (1) summary
      pfam01593
      Location:45 → 193
      Amino_oxidase; Flavin containing amine oxidoreductase

    8. NM_001177840.2 → NP_001171311.1  spermine oxidase isoform i

      See identical proteins and their annotated locations for NP_001171311.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) lacks four alternate exons but maintains the reading frame, compared to variant 1. The resulting protein (isoform i) is shorter when it is compared to isoform a. This transcript has also been called 'splice variant delta'.
      Source sequence(s)
      AL831731, AL831781
      Consensus CDS
      CCDS50725.1
      UniProtKB/Swiss-Prot
      Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Related
      ENSMUSP00000105811.3, ENSMUST00000110182.9
      Conserved Domains (1) summary
      pfam13450
      Location:45 → 88
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    9. NM_145533.3 → NP_663508.1  spermine oxidase isoform b

      See identical proteins and their annotated locations for NP_663508.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate, in-frame, exon, compared to variant 1. The resulting protein (isoform b) is shorter when it is compared to isoform a. This transcript and protein have also been called 'polyamine oxidase-l'.
      Source sequence(s)
      AL831731, AL831781
      Consensus CDS
      CCDS16763.1
      UniProtKB/Swiss-Prot
      A2ANQ8, A2ANQ9, A2ANR0, A2ANR1, A2ANR2, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57, Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Related
      ENSMUSP00000028806.6, ENSMUST00000028806.12
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 548
      PLN02568; polyamine oxidase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      131333624..131367103
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161366.1 → XP_036017259.1  spermine oxidase isoform X2

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 577
      PLN02568; polyamine oxidase

    2. XM_036161365.1 → XP_036017258.1  spermine oxidase isoform X1

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 578
      PLN02568; polyamine oxidase

    3. XM_036161371.1 → XP_036017264.1  spermine oxidase isoform X3

      UniProtKB/Swiss-Prot
      A2ANQ8, A2ANQ9, A2ANR0, A2ANR1, A2ANR2, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57, Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 548
      PLN02568; polyamine oxidase

    4. XM_006499290.3 → XP_006499353.1  spermine oxidase isoform X5

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 513
      PLN02568; polyamine oxidase

    5. XM_006499293.4 → XP_006499356.1  spermine oxidase isoform X12

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 403
      PLN02568; polyamine oxidase

    6. XM_017317769.2 → XP_017173258.1  spermine oxidase isoform X14

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 373
      PLN02568; polyamine oxidase

    7. XM_030250476.2 → XP_030106336.1  spermine oxidase isoform X4

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 547
      PLN02568; polyamine oxidase

    8. XM_006499291.2 → XP_006499354.1  spermine oxidase isoform X8

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 442
      PLN02568; polyamine oxidase

    9. XM_036161395.1 → XP_036017288.1  spermine oxidase isoform X15

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 266
      PLN02568; polyamine oxidase

    10. XM_006499289.5 → XP_006499352.1  spermine oxidase isoform X2

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 577
      PLN02568; polyamine oxidase

    11. XM_006499287.4 → XP_006499350.1  spermine oxidase isoform X1

      See identical proteins and their annotated locations for XP_006499350.1

      UniProtKB/Swiss-Prot
      Q99K82
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 578
      PLN02568; polyamine oxidase

    12. XM_030250468.1 → XP_030106328.1  spermine oxidase isoform X3

      UniProtKB/Swiss-Prot
      A2ANQ8, A2ANQ9, A2ANR0, A2ANR1, A2ANR2, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57, Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 548
      PLN02568; polyamine oxidase

    13. XM_030250500.1 → XP_030106360.1  spermine oxidase isoform X11

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 411
      PLN02568; polyamine oxidase

    14. XM_011239475.3 → XP_011237777.1  spermine oxidase isoform X16

      Conserved Domains (2) summary
      PLN02568
      Location:226 → 271
      PLN02568; polyamine oxidase
      pfam01593
      Location:45 → 115
      Amino_oxidase; Flavin containing amine oxidoreductase

    15. XM_030250509.1 → XP_030106369.1  spermine oxidase isoform X13

      Conserved Domains (1) summary
      PLN02568
      Location:43 → 400
      PLN02568; polyamine oxidase

    16. XM_030250487.2 → XP_030106347.1  spermine oxidase isoform X7

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 444
      PLN02568; polyamine oxidase

    17. XM_006499292.4 → XP_006499355.1  spermine oxidase isoform X9

      Conserved Domains (1) summary
      PLN02568
      Location:43 → 430
      PLN02568; polyamine oxidase

    18. XM_036161370.1 → XP_036017263.1  spermine oxidase isoform X3

      UniProtKB/Swiss-Prot
      A2ANQ8, A2ANQ9, A2ANR0, A2ANR1, A2ANR2, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57, Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 548
      PLN02568; polyamine oxidase

    19. XM_036161383.1 → XP_036017276.1  spermine oxidase isoform X10

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 412
      PLN02568; polyamine oxidase

    20. XM_036161363.1 → XP_036017256.1  spermine oxidase isoform X1

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 578
      PLN02568; polyamine oxidase

    21. XM_036161400.1 → XP_036017293.1  spermine oxidase isoform X17

      UniProtKB/TrEMBL
      A2ANQ4
      Conserved Domains (1) summary
      pfam01593
      Location:45 → 193
      Amino_oxidase; Flavin containing amine oxidoreductase

    22. XM_036161361.1 → XP_036017254.1  spermine oxidase isoform X1

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 578
      PLN02568; polyamine oxidase

    23. XM_030250513.2 → XP_030106373.1  spermine oxidase isoform X17

      UniProtKB/TrEMBL
      A2ANQ4
      Conserved Domains (1) summary
      pfam01593
      Location:45 → 193
      Amino_oxidase; Flavin containing amine oxidoreductase

    24. XM_030250472.2 → XP_030106332.1  spermine oxidase isoform X3

      UniProtKB/Swiss-Prot
      A2ANQ8, A2ANQ9, A2ANR0, A2ANR1, A2ANR2, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57, Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 548
      PLN02568; polyamine oxidase

    25. XM_036161368.1 → XP_036017261.1  spermine oxidase isoform X3

      UniProtKB/Swiss-Prot
      A2ANQ8, A2ANQ9, A2ANR0, A2ANR1, A2ANR2, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57, Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 548
      PLN02568; polyamine oxidase

    26. XM_030250470.1 → XP_030106330.1  spermine oxidase isoform X3

      UniProtKB/Swiss-Prot
      A2ANQ8, A2ANQ9, A2ANR0, A2ANR1, A2ANR2, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57, Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 548
      PLN02568; polyamine oxidase

    27. XM_006499288.3 → XP_006499351.1  spermine oxidase isoform X1

      See identical proteins and their annotated locations for XP_006499351.1

      UniProtKB/Swiss-Prot
      Q99K82
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 578
      PLN02568; polyamine oxidase

    28. XM_030250486.1 → XP_030106346.1  spermine oxidase isoform X6

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 445
      PLN02568; polyamine oxidase

    29. XM_030250494.1 → XP_030106354.1  spermine oxidase isoform X8

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 442
      PLN02568; polyamine oxidase

    30. XM_030250498.1 → XP_030106358.1  spermine oxidase isoform X10

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 412
      PLN02568; polyamine oxidase

    31. XM_036161392.1 → XP_036017285.1  spermine oxidase isoform X12

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 403
      PLN02568; polyamine oxidase

    32. XM_030250511.2 → XP_030106371.1  spermine oxidase isoform X17

      UniProtKB/TrEMBL
      A2ANQ4
      Conserved Domains (1) summary
      pfam01593
      Location:45 → 193
      Amino_oxidase; Flavin containing amine oxidoreductase

    33. XM_030250481.1 → XP_030106341.1  spermine oxidase isoform X4

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 547
      PLN02568; polyamine oxidase

    34. XM_036161362.1 → XP_036017255.1  spermine oxidase isoform X1

      Conserved Domains (1) summary
      PLN02568
      Location:50 → 578
      PLN02568; polyamine oxidase

    35. XM_036161369.1 → XP_036017262.1  spermine oxidase isoform X3

      UniProtKB/Swiss-Prot
      A2ANQ8, A2ANQ9, A2ANR0, A2ANR1, A2ANR2, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57, Q99K82
      UniProtKB/TrEMBL
      Q3UPW5
      Conserved Domains (1) summary
      PLN02568
      Location:50 → 548
      PLN02568; polyamine oxidase

    RNA

    1. XR_374452.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99K82.1 GenPept UniProtKB/Swiss-Prot:Q99K82

    Gene LinkOut

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