Cox7b cytochrome c oxidase subunit 7B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cox7bprovided by MGI
Official Full Name: cytochrome c oxidase subunit 7Bprovided by MGI
Primary source: MGI:MGI:1913392
See related: Ensembl:ENSMUSG00000031231 AllianceGenome:MGI:1913392
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1110004F07Rik
Summary: Predicted to be involved in central nervous system development. Located in mitochondrion. Part of respiratory chain complex IV. Is active in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; heart; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 2. Orthologous to human COX7B (cytochrome c oxidase subunit 7B). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in heart adult (RPKM 288.1), liver E18 (RPKM 161.7) and 25 other tissues See more
Orthologs: human all
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Genomic context

Location:: X D; X 47.36 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (105059306..105066056)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (106015700..106022450)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH126945 (e-PCR)
- UniSTS:209769

Cox7b (e-PCR), detects polymorphism
- UniSTS:499176

NoName (e-PCR)
- UniSTS:238067

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in central nervous system development	ISO Inferred from Sequence Orthology more info
involved_in central nervous system development	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial electron transport, cytochrome c to oxygen	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrial inner membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrial membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IDA Inferred from Direct Assay more info	PubMed
part_of respiratory chain complex IV	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: cytochrome c oxidase subunit 7B, mitochondrial

Names: cytochrome c oxidase polypeptide VIIb; cytochrome c oxidase subunit VIIb

NP_079655.1

EC 7.1.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.