U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    oys oysgedart [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36045, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    oysprovided by FlyBase
    Official Full Name
    oysgedartprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033476
    Locus tag
    Dmel_CG18445
    See related
    AllianceGenome:FB:FBgn0033476
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG18445; Dmel\CG18445; Oys
    Summary
    Enables lysophospholipid acyltransferase activity. Involved in several processes, including germ cell migration; lipid modification; and sperm individualization. Located in membrane. Is expressed in adult head; male germline cell; and organism. Orthologous to human MBOAT1 (membrane bound O-acyltransferase domain containing 1) and MBOAT2 (membrane bound O-acyltransferase domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See oys in Genome Data Viewer
    Location:
    46D7-46D8; 2-61 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10034595..10048619, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5922100..5936124, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44294 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44295 Neighboring gene uncharacterized protein Neighboring gene Cytochrome c oxidase subunit 7C Neighboring gene antisense RNA:CR44297 Neighboring gene Cytochrome c oxidase subunit 7C-like Neighboring gene seele Neighboring gene magu

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Drosophila lysophospholipid acyltransferases are specifically required for germ cell development. Steinhauer J, et al. Mol Biol Cell, 2009 Dec. PMID 19864461, Free PMC Article
    2. Drosophila spermatid individualization is sensitive to temperature and fatty acid metabolism. Ben-David G, et al. Spermatogenesis, 2015 Jan-Apr. PMID 26413411, Free PMC Article
    3. Drosophila Pif1A is essential for spermatogenesis and is the homolog of human CCDC157, a gene associated with idiopathic NOA. Yuan X, et al. Cell Death Dis, 2019 Feb 11. PMID 30741974, Free PMC Article
    4. Drosophila mini-white model system: new insights into positive position effects and the role of transcriptional terminators and gypsy insulator in transgene shielding. Silicheva M, et al. Nucleic Acids Res, 2010 Jan. PMID 19854952, Free PMC Article
    5. Drosophila model for studying the link between lipid metabolism and development. Thanh MT, et al. Front Biosci (Landmark Ed), 2020 Jan 1. PMID 31585882

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lysophospholipid acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in germ cell migration IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in lipid modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lipid modification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in plasma membrane organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in sperm individualization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    oysgedart
    Names
    CG18445-PA
    CG18445-PB
    CG18445-PD
    CG18445-PE
    O-acyl transferase
    oys-PA
    oys-PB
    oys-PD
    oys-PE
    NP_001286265.1
    NP_001286266.1
    NP_001286267.1
    NP_610546.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10034595..10048619 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299338.1 → NP_001286267.1  oysgedart, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286267.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0B4LG01, Q6NN55
      Conserved Domains (1) summary
      cl00738
      Location:22 → 484
      MBOAT; membrane-bound O-acyltransferase family

    2. NM_001299336.1 → NP_001286265.1  oysgedart, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286265.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0B4LG01, Q6NN55
      Conserved Domains (1) summary
      cl00738
      Location:22 → 484
      MBOAT; membrane-bound O-acyltransferase family

    3. NM_001299337.1 → NP_001286266.1  oysgedart, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286266.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LG01
      Conserved Domains (1) summary
      cl00738
      Location:4 → 464
      MBOAT; MBOAT, membrane-bound O-acyltransferase family

    4. NM_136702.3 → NP_610546.1  oysgedart, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610546.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0B4LG01, Q6NN55
      Related
      FBpp0087520
      Conserved Domains (1) summary
      cl00738
      Location:22 → 484
      MBOAT; membrane-bound O-acyltransferase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NN55.1 Q6NN55
    Q8T8Q2 Q8T8Q2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous